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5-Nonyloxytryptamine oxalate (CAS 157798-13-5)

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Alternate Names:
2-[5-(nonyloxy)-1H-indol-3-yl]ethanamine ethanedioate
Application:
5-Nonyloxytryptamine oxalate is a selective agonist for SR-1B
CAS Number:
157798-13-5
Purity:
≥98%
Molecular Weight:
392.49
Molecular Formula:
C19H30N2O•C2H2O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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5-HT1B selective agonist, several times more potent than sumatriptan and inactive as a 5-HT1A agonist (Ki at 5-HT1B = 1 nM, selectivity over 5-HT1A > 300-fold).


5-Nonyloxytryptamine oxalate (CAS 157798-13-5) References

  1. Nonyloxytryptamine mimics polysialic acid and modulates neuronal and glial functions in cell culture.  |  Loers, G., et al. 2014. J Neurochem. 128: 88-100. PMID: 23957498
  2. Small-molecule based musculoskeletal regenerative engineering.  |  Lo, KW., et al. 2014. Trends Biotechnol. 32: 74-81. PMID: 24405851
  3. The polysialic acid mimetics 5-nonyloxytryptamine and vinorelbine facilitate nervous system repair.  |  Saini, V., et al. 2016. Sci Rep. 6: 26927. PMID: 27324620
  4. The neuroplasticity marker PSA-NCAM: Insights into new therapeutic avenues for promoting neuroregeneration.  |  Saini, V., et al. 2020. Pharmacol Res. 160: 105186. PMID: 32898689
  5. Targeting sialylation to treat central nervous system diseases.  |  Lünemann, JD., et al. 2021. Trends Pharmacol Sci. 42: 998-1008. PMID: 34607695
  6. 5-(Nonyloxy)tryptamine: a novel high-affinity 5-HT1D beta serotonin receptor agonist.  |  Glennon, RA., et al. 1994. J Med Chem. 37: 2828-30. PMID: 8071931
  7. Binding of O-alkyl derivatives of serotonin at human 5-HT1D beta receptors.  |  Glennon, RA., et al. 1996. J Med Chem. 39: 314-22. PMID: 8568822

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

5-Nonyloxytryptamine oxalate, 10 mg

sc-203480
10 mg
$113.00

5-Nonyloxytryptamine oxalate, 50 mg

sc-203480A
50 mg
$640.00