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Fisetin is a flavone which acts as an inhibitor of Akt, Cdk6, mTOR and PI 3-kinase and an activator of ERK. It may act to inhibit melanoma cell growth via its mTOR binding activity. Fisetin exhibits a high affinity for DNA binding, effectively inhibiting transcriptional activity by blocking the binding of RNA polymerase II. Furthermore, it demonstrates the ability to inhibit hydrogen peroxide-induced lipid peroxidation in vitro.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
5-Nitro-2-[(thien-2-ylmethyl)amino]benzonitrile, 500 mg | sc-318978 | 500 mg | $180.00 |