Date published: 2026-6-1

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5-Methylsalicylic acid (CAS 89-56-5)

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Alternate Names:
p-Cresotic acid
CAS Number:
89-56-5
Purity:
97%
Molecular Weight:
152.15
Molecular Formula:
C8H8O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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5-Methylsalicylic acid is used in analytical chemistry to detect p-hydroxybenzoic acid in urine samples. It has protocatechuic acid, hydrochloric acid, and cationic surfactant characteristics. It demonstrates diphenolase activity and can be used as an antioxidant. 5-Methylsalicylic acid can be found in plants like nepeta cataria or sephadex g-100. In addition, this acid shows significant cross-reactivity during fluorescent polarization immunoassay for salicylates in serum.


5-Methylsalicylic acid (CAS 89-56-5) References

  1. A solvent-controlled switch of manganese complex assemblies with a beta-diketonate-based ligand.  |  Aromí, G., et al. 2002. Inorg Chem. 41: 3673-83. PMID: 12099871
  2. Rate and extent of ion-exchange process: the effect of physico-chemical characteristics of salicylate anions.  |  Hänninen, K., et al. 2003. J Control Release. 91: 449-63. PMID: 12932722
  3. Elucidating magnetic exchange and anisotropy in weakly coupled Mn(III) dimers.  |  Liu, J., et al. 2013. Inorg Chem. 52: 718-23. PMID: 23273268
  4. Organic additive, 5-methylsalicylic acid induces spontaneous structural transformation of aqueous pluronic triblock copolymer solution: a spectroscopic investigation of interaction of curcumin with pluronic micellar and vesicular aggregates.  |  Ghosh, S., et al. 2014. J Phys Chem B. 118: 11437-48. PMID: 25192258
  5. Functionalization of Single-walled Carbon Nanotubes with Thermo-reversible Block Copolymers and Characterization by Small-angle Neutron Scattering.  |  Han, Y., et al. 2016. J Vis Exp.. PMID: 27285590
  6. Novel Salicylic Acid Analogs Induce a Potent Defense Response in Arabidopsis.  |  Palmer, IA., et al. 2019. Int J Mol Sci. 20: PMID: 31288496
  7. Dextro-gamma-carboxymethyl-gamma-methyl-delta-alpha-butenolide. A 1,2-ring-fission product of 4-methylcatechol by Pseudomonas desmolyticum.  |  Catelani, D., et al. 1971. Biochem J. 121: 89-92. PMID: 5116566
  8. Effect of substitution on the photoinduced intramolecular proton transfer in salicylic acid  |  Lahmani, F., & Zehnacker-Rentien, A. 1997. The Journal of Physical Chemistry A. 101(35): 6141-6147.
  9. Spectroscopic studies of solid-state forms of donepezil free base and salt forms with various salicylic acids  |  Brittain, H. G. 2014. Journal of Molecular Structure. 1078: 207-212.
  10. Tunable encapsulation structure of block copolymer coated single-walled carbon nanotubes in aqueous solution  |  Han, Y., Ahn, S. K., Zhang, Z., Smith, G. S., & Do, C. 2015. Macromolecules. 48(11): 3475-3480.
  11. Anomalistic self-assembled phase behavior of block copolymer blended with organic derivative depending on temperature  |  Kim, T. H., Kim, E., Do, C., Ahn, H., Lee, H., & Han, Y. S. 2016. Macromolecules. 49(17): 6541-6548.
  12. Scalable photoelectrochromic glass of high performance powered by ligand attached TiO2 photoactive layer  |  Sarwar, S., Park, S., Dao, T. T., Lee, M. S., Ullah, A., Hong, S., & Han, C. H. 2020. Solar Energy Materials and Solar Cells. 210: 110498.
  13. Influence of Hydroxyl Group Position and Substitution Pattern of Hydroxybenzoic Acid on the Formation of Molecular Salts with the Antifolate Pyrimethamine  |  Ceborska, M., Kędra-Królik, K., Narodowiec, J., & Dąbrowa, K. 2021. Crystal Growth & Design. 21(12): 6714-6726.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

5-Methylsalicylic acid, 10 g

sc-239064
10 g
$66.00