Date published: 2026-4-27

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5-Maleimido-eosin (CAS 75350-45-7)

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Alternate Names:
Eosin-5-maleimide
Application:
5-Maleimido-eosin is a triplet probe
CAS Number:
75350-45-7
Purity:
≥93%
Molecular Weight:
742.95
Molecular Formula:
C24H9Br4NO7
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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5-Maleimido-eosin is primarily utilized in the field of bioconjugation, where it is used to label proteins and peptides with fluorescent probes. This compound specifically targets and reacts with thiol groups on cysteine residues, allowing for specific and efficient tagging of biomolecules. This specificity is particularly useful in fluorescence microscopy, where 5-Maleimido-eosin-labeled compounds enable researchers to visualize and track the behavior and interaction of proteins within cells under various conditions. Additionally, 5-Maleimido-eosin is employed in the study of protein folding and structure, providing insights into protein dynamics and mechanisms of action. Its application extends into the development of diagnostic tools, where it enhances the detection capabilities of biomolecular assays through fluorescence, aiding in the study of disease mechanisms and cellular processes.


5-Maleimido-eosin (CAS 75350-45-7) References

  1. Impact of Payload Hydrophobicity on the Stability of Antibody-Drug Conjugates.  |  Buecheler, JW., et al. 2018. Mol Pharm. 15: 2656-2664. PMID: 29809017

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

5-Maleimido-eosin, 10 mg

sc-210356
10 mg
$238.00

5-Maleimido-eosin, 25 mg

sc-210356A
25 mg
$430.00