Date published: 2025-10-19

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5-Isopropyl-2-methylphenol (CAS 499-75-2)

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Alternate Names:
Carvacrol
CAS Number:
499-75-2
Molecular Weight:
150.22
Molecular Formula:
C10H14O
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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5-Isopropyl-2-methylphenol, also known as Carvacrol, is a naturally occurring monoterpene phenol present in essential oils. It is prominently found in oregano, thyme, rosemary, and various other herbs and spices. 5-Isopropyl-2-methylphenol has been used for centuries as a natural remedy for various ailments and has recently gained recognition for its potential antimicrobial, antifungal, and antioxidant properties. Research studies have demonstrated that 5-Isopropyl-2-methylphenol exhibits inhibitory effects on the growth of diverse bacteria, including Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa. It has also shown efficacy against a range of fungi, such as Candida albicans, Aspergillus niger, and Trichophyton mentagrophytes. Additionally, 5-Isopropyl-2-methylphenol possesses antioxidant activity, contributing to cellular protection against oxidative stress. The precise mechanism of action of 5-Isopropyl-2-methylphenol is not yet fully elucidated however, it is hypothesized that 5-Isopropyl-2-methylphenol disrupts the cell membrane of bacteria and fungi, leading to their demise. Moreover, 5-Isopropyl-2-methylphenol has exhibited the ability to impede virus growth by inhibiting viral replication.


5-Isopropyl-2-methylphenol (CAS 499-75-2) References

  1. Carvacrol Induces Candida albicans Apoptosis Associated With Ca2+/Calcineurin Pathway.  |  Niu, C., et al. 2020. Front Cell Infect Microbiol. 10: 192. PMID: 32426298
  2. Carvacrol may alleviate vascular inflammation in diabetic db/db mice.  |  Zhao, W., et al. 2020. Int J Mol Med. 46: 977-988. PMID: 32583003
  3. Carvacrol exhibits rapid bactericidal activity against Streptococcus pyogenes through cell membrane damage.  |  Wijesundara, NM., et al. 2021. Sci Rep. 11: 1487. PMID: 33452275
  4. Carvacrol-loaded liposome suspension: optimization, characterization and incorporation into poly(vinyl alcohol) films.  |  Tavares, AG., et al. 2021. Food Funct. 12: 6549-6557. PMID: 34096962
  5. Protective effect of carvacrol on liver injury in type 2 diabetic db/db mice.  |  Zhao, W., et al. 2021. Mol Med Rep. 24: PMID: 34435648
  6. Carvacrol Suppresses Human Osteosarcoma Cells via the Wnt/β-Catenin Signaling Pathway.  |  Zhang, S., et al. 2022. Anticancer Agents Med Chem. 22: 1714-1722. PMID: 34488595
  7. Carvacrol modulates the expression and activity of antioxidant enzymes in Candida auris.  |  Ismail, M., et al. 2022. Res Microbiol. 173: 103916. PMID: 34863882
  8. Carvacrol reduces blood pressure, arterial responsiveness and increases expression of MAS receptors in spontaneously hypertensive rats.  |  Dias, CJ., et al. 2022. Eur J Pharmacol. 917: 174717. PMID: 34953800
  9. The protective effect of carvacrol on acetaminophen-induced renal damage in male rats.  |  Najafizadeh, A., et al. 2022. Mol Biol Rep. 49: 1763-1771. PMID: 35020122
  10. Carvacrol Suppresses Inflammatory Biomarkers Production by Lipoteichoic Acid- and Peptidoglycan-Stimulated Human Tonsil Epithelial Cells.  |  Wijesundara, NM., et al. 2022. Nutrients. 14: PMID: 35276864
  11. Carvacrol Enhances the Antimicrobial Potency of Berberine in Bacillus subtilis.  |  Atas, B., et al. 2022. Curr Microbiol. 79: 135. PMID: 35303184
  12. Carvacrol Alleviates Hyperuricemia-Induced Oxidative Stress and Inflammation by Modulating the NLRP3/NF-κB Pathwayt.  |  Riaz, M., et al. 2022. Drug Des Devel Ther. 16: 1159-1170. PMID: 35496367
  13. Perimeter and carvacrol-loading regulate angiogenesis and biofilm growth in 3D printed PLA scaffolds.  |  Farto-Vaamonde, X., et al. 2022. J Control Release. 352: 776-792. PMID: 36336096
  14. Unraveling the Biosynthesis of Carvacrol in Different Tissues of Origanum vulgare.  |  Hao, Y., et al. 2022. Int J Mol Sci. 23: PMID: 36362019
  15. Carvacrol Inhibits Expression of Transient Receptor Potential Melastatin 7 Channels and Alleviates Zinc Neurotoxicity Induced by Traumatic Brain Injury.  |  Lee, M., et al. 2022. Int J Mol Sci. 23: PMID: 36430333

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

5-Isopropyl-2-methylphenol, 25 g

sc-357863
25 g
$56.00

5-Isopropyl-2-methylphenol, 100 g

sc-357863A
100 g
$152.00

5-Isopropyl-2-methylphenol, 500 g

sc-357863B
500 g
$435.00