Molecular structure of 5-Iodocytidine, CAS Number: 1147-23-5
5-Iodocytidine (CAS 1147-23-5)
Application:
5-Iodocytidine is a key tool for research in the field of nucleic acids and nucleic acid-protein interactions
CAS Number:
1147-23-5
Purity:
≥99%
Molecular Weight:
369.1
Molecular Formula:
C9H12IN3O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
5-Iodocytidine is a key tool for research in the field of nucleic acids and nucleic acid-protein interactions. Has been used in structural elucidation of mispairs with natural bases to explain their mutagenic properties; in the study of cytosine methyltransferases; 5-Iodocytidine has also been used for photo-crosslinking of nucleoprotein complexes; in X-ray diffraction experiments of nucleic acids and nucleic acid binding proteins; as nonradioactive label and as alternative for mixed probes; for triple-helix stabilization; as antisense oligonucleotide; and in the study of the restriction endonucleases cleavage mechanism.
5-Iodocytidine (CAS 1147-23-5) References
1. Complex of aspartate carbamoyltransferase from Escherichia coli with its allosteric inhibitor, cytidine triphosphate: electron density at 5.9-angstroms resolution: B.F. Edwards, et al.; PNAS 71, 4437 (1974). 2. Properties of phenylalanine transfer ribonucleic acid with modified 3'-terminal end in protein biosynthesis using a rabbit reticulocyte cell-free system: effect of the replacement of cytidine residues from the CpCpA end of tRNA by 5-iodocytidine or : E.K. Baksht, et al.; Nucl. Acids Res. 4, 2205 (1977). 3. Photocrosslinking of 5-iodouracil-substituted RNA and DNA to proteins: M.C. Willis, et al.; Science 262, 1255 (1993). 4. High yield photocrosslinking of a 5-iodocytidine (IC) substituted RNA to its associated protein: K.M. Meisenheimer, et al.; Nucl. Acids Res. 24, 981 (1996). 5. Preparation and properties of oligodeoxynucleotides containing 5-iodouracil and 5-bromo- and 5-iodocytosine: E. Ferrer, et al.; Bioconjug. Chem. 8, 757 (1997).Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
5-Iodocytidine, 5 mg | sc-202426 | 5 mg | $60.00 | |||
5-Iodocytidine, 25 mg | sc-202426A | 25 mg | $125.00 |