Molecular structure of 5-Hydroxymethyl-2-furaldehyde, CAS Number: 67-47-0
5-Hydroxymethyl-2-furaldehyde (CAS 67-47-0)
See product citations (2)
Alternate Names:
5-(Hydroxymethyl)furfural
Application:
5-Hydroxymethyl-2-furaldehyde is an antioxidant found in some fruit juices
CAS Number:
67-47-0
Molecular Weight:
126.11
Molecular Formula:
C6H6O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Product Citations
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
5-Hydroxymethyl-2-furaldehyde (HMF) is extensively researched due to its potential applications in biotechnology. It is a simple organic compound with a furan ring attached to a hydroxymethyl group. 5-Hydroxymethyl-2-furaldehyde occurs naturally through carbohydrate dehydration (such as fructose and glucose) or synthesis using formaldehyde and glycols. It is used to inhibit the formation of reactive oxygen species (ROS) and scavenge free radicals. Moreover, it has the ability to modulate the activity of enzymes and proteins involved in oxidative stress and inflammation.
5-Hydroxymethyl-2-furaldehyde (CAS 67-47-0) References
- Supercritical fluid extraction of 5-hydroxymethyl-2-furaldehyde from raisins. | Palma, M. and Taylor, LT. 2001. J Agric Food Chem. 49: 628-32. PMID: 11262003
- Thermal decomposition of 5-(hydroxymethyl)-2-furaldehyde (HMF) and its further transformations in the presence of glycine. | Nikolov, PY. and Yaylayan, VA. 2011. J Agric Food Chem. 59: 10104-13. PMID: 21838257
- Solvent effect on pathways and mechanisms for D-fructose conversion to 5-hydroxymethyl-2-furaldehyde: in situ 13C NMR study. | Kimura, H., et al. 2013. J Phys Chem A. 117: 2102-13. PMID: 23458365
- Short communication: possible mechanism for inhibiting the formation of polymers originated from 5-hydroxymethyl-2-furaldehyde by sulfite groups in the dairy thermal process. | Guan, YG., et al. 2013. J Dairy Sci. 96: 2826-31. PMID: 23498013
- 5-(Hydroxymethyl)-2-furaldehyde inhibits adipogenic and enhances osteogenic differentiation of rat bone mesenchymal stem cells. | Tan, XL., et al. 2014. Nat Prod Commun. 9: 529-32. PMID: 24868876
- Pretreatment with 5-hydroxymethyl-2-furaldehyde blocks scopolamine-induced learning deficit in contextual and spatial memory in male mice. | Lee, Y., et al. 2015. Pharmacol Biochem Behav. 134: 57-64. PMID: 25922228
- 5-hydroxymethyl-2-furaldehyde from marine bacterium Bacillus subtilis inhibits biofilm and virulence of Candida albicans. | Subramenium, GA., et al. 2018. Microbiol Res. 207: 19-32. PMID: 29458854
- Exploring the binding interaction of Maillard reaction by-product 5-hydroxymethyl-2-furaldehyde with calf thymus DNA. | Zhou, Z., et al. 2019. J Sci Food Agric. 99: 3192-3202. PMID: 30548611
- 5-hydroxymethyl-2-furaldehyde purified from Japanese pear (Pyrus pyrifolia Nakai cv. Nijisseiki) juice concentrate inhibits melanogenesis in B16 mouse melanoma cells. | Bito, T., et al. 2020. Biosci Biotechnol Biochem. 84: 2374-2384. PMID: 32674671
- Reasons for 2-furaldehyde and 5-hydroxymethyl-2-furaldehyde resistance in Saccharomyces cerevisiae: current state of knowledge and perspectives for further improvements. | Liu, ZL. 2021. Appl Microbiol Biotechnol. 105: 2991-3007. PMID: 33830300
- 5-hydroxymethyl-2-furaldehyde impairs Candida albicans - Staphylococcus epidermidis interaction in co-culture by suppressing crucial supportive virulence traits. | Swetha, TK., et al. 2021. Microb Pathog. 158: 104990. PMID: 34048889
- 5-Hydroxymethyl-2-furaldehyde induces developmental toxicology and decreases bone mineralization in zebrafish larvae. | Jiang, Y., et al. 2022. Comp Biochem Physiol C Toxicol Pharmacol. 254: 109254. PMID: 34971842
- Bioactivation of 5-hydroxymethyl-2-furaldehyde to an electrophilic and mutagenic allylic sulfuric acid ester. | Lee, YC., et al. 1995. Biochem Biophys Res Commun. 209: 996-1002. PMID: 7733994
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
5-Hydroxymethyl-2-furaldehyde, 5 g | sc-210345 | 5 g | $250.00 |