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(S)-Equol is a non-steroidal estrogen. The estrogen receptor (ER) agonist activity of the occurring (S)-enantiomer (EC50 = 85 and 65 nM for ERalpha and ERbeta, respectively) is similar to that of genistein but exceeds that of daidzein. (S)-Equol preferentially binds ERbeta (Ki = 0.73 nM) and demonstrates approximately 9-fold lower affinity for ERalpha (Ki = 6.41 nM). Also a potent antagonist of dihydrotestosterone, which has important implications for prostate cancer and other androgen-mediated pathologies.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
[(5-Hydroxy-pyridine-3-carbonyl)-amino]-acetic acid, 500 mg | sc-318806 | 500 mg | $240.00 |