Molecular structure of 5-Hydroxy Dantrolene, CAS Number: 52130-25-3
5-Hydroxy Dantrolene (CAS 52130-25-3)
Alternate Names:
5-Hydroxy-1-[[[5-(4-nitrophenyl)-2-furanyl]methylene]amino]-2,4-imidazolidinedione
Application:
5-Hydroxy Dantrolene is A metabolite of Dantrolene
CAS Number:
52130-25-3
Purity:
98%
Molecular Weight:
330.25
Molecular Formula:
C14H10N4O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
5-Hydroxy Dantrolene is a metabolite of Dantrolene, and has shown to have muscle relaxant effects. 5-Hydroxy Dantrolene exhibits a diverse range of beneficial properties, including anti-inflammatory, anti-cancer, and neuroprotective effects. Moreover, it has been demonstrated to regulate calcium signaling, a process involved in multiple physiological functions. Extensive research has focused on investigating the potential of 5-Hydroxy Dantrolene in the fields of cardiovascular diseases, neurodegenerative disorders, and cancer.
5-Hydroxy Dantrolene (CAS 52130-25-3) References
- Pharmacokinetics and metabolism of dantrolene in horses. | DiMaio Knych, HK., et al. 2011. J Vet Pharmacol Ther. 34: 238-46. PMID: 21492188
- Counter-flow suggests transport of dantrolene and 5-OH dantrolene by the organic anion transporters 2 (OAT2) and 3 (OAT3). | Burckhardt, BC., et al. 2016. Pflugers Arch. 468: 1909-1918. PMID: 27812757
- Simultaneous determination of dantrolene and its metabolites, 5-hydroxydantrolene and nitro-reduced acetylated dantrolene (F 490), in plasma and urine of man and dog by high-performance liquid chromatography. | Wuis, EW., et al. 1982. J Chromatogr. 231: 401-9. PMID: 7130316
- The effect of dantrolene sodium in relation to blood levels in spastic patients after prolonged administration. | Meyler, WJ., et al. 1981. J Neurol Neurosurg Psychiatry. 44: 334-9. PMID: 7241161
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
5-Hydroxy Dantrolene, 2 mg | sc-207032B | 2 mg | $239.00 | |||
5-Hydroxy Dantrolene, 2 mg | sc-207032B-CW | 2 mg | $447.00 | |||
5-Hydroxy Dantrolene, 5 mg | sc-207032 | 5 mg | $480.00 | |||
5-Hydroxy Dantrolene, 10 mg | sc-207032A | 10 mg | $844.00 | |||
5-Hydroxy Dantrolene, 25 mg | sc-207032C | 25 mg | $1900.00 | |||
5-Hydroxy Dantrolene, 50 mg | sc-207032D | 50 mg | $3500.00 |