Molecular structure of 5-Fluorouracil-13C,15N2, CAS Number: 1189423-58-2
5-Fluorouracil-13C,15N2 (CAS 1189423-58-2)
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Alternate Names:
5-Fluorodihydropyrimidine-2,4-dione-13C,15N2
Application:
5-Fluorouracil-13C,15N2 is an isotopically labeled inhibitor of DNA synthesis
CAS Number:
1189423-58-2
Molecular Weight:
133.06
Molecular Formula:
C3(13C)H3F(15N)2O2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
5-Fluorouracil-13C,15N2 is an isotopically labeled inhibitor of DNA synthesis. 5-Fluorouracil-13C,15N2 serves as an internal standard for the quantification of 5-fluorouracil using GC- or LC-MS. 5-Fluorouracil, a pyrimidine analog, effectively hinders the activity of thymidylate synthase, an enzyme for thymidine synthesis necessary for DNA replication. The intracellular metabolites of 5-fluorouracil exert their cytotoxic effects through two mechanisms: either by inhibiting thymidylate synthetase or by incorporating themselves into RNA and DNA molecules, consequently initiating the process of programmed cell death, known as apoptosis.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
5-Fluorouracil-13C,15N2, 1 mg | sc-217189 | 1 mg | $418.00 |