Date published: 2026-6-26

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5-Fluoro-D,L-tryptophan (CAS 154-08-5)

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Alternate Names:
DL-2-Amino-3-(5-fluoro-1H-indol-3-yl)propanoic acid
CAS Number:
154-08-5
Molecular Weight:
222.22
Molecular Formula:
C11H11FN2O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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5-Fluoro-D,L-tryptophan (5-FT) is a derivative of the amino acid tryptophan, widely investigated for its applications in scientific research. As a fluorinated variant of tryptophan, which is an indispensable amino acid present in proteins, 5-Fluorotryptophan serves as an effective inhibitor of enzymes and receptors. By binding to the active site of these enzymes or receptors, it obstructs the attachment of the substrate or ligand. Consequently, the normal functioning of the enzyme or receptor is impeded.


5-Fluoro-D,L-tryptophan (CAS 154-08-5) References

  1. Sensitive high-performance liquid chromatographic assay for D-amino-acid oxidase activity in mammalian tissues using a fluorescent non-natural substrate, 5-fluoro-D-tryptophan.  |  Hamase, K., et al. 2006. J Chromatogr A. 1106: 159-64. PMID: 16443460
  2. 5-fluoro-D,L-tryptophan as a dual NMR and fluorescent probe of α-synuclein.  |  Pfefferkorn, CM. and Lee, JC. 2012. Methods Mol Biol. 895: 197-209. PMID: 22760321
  3. Plant growth-stimulating rhizobacteria capable of producing L-amino acids.  |  Pizarro-Tobias, P., et al. 2020. Environ Microbiol Rep. 12: 667-671. PMID: 32940018

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

5-Fluoro-D,L-tryptophan, 1 g

sc-217184
1 g
$374.00