5-Diethylaminomethyl-furan-3-carboxylic acid hydrochloride
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MRS 3777 hemioxalate is a compound that functions as a selective antagonist of the metabotropic glutamate receptor subtype 2 (mGlu2). It acts by binding to the orthosteric site of the receptor, thereby inhibiting its activation by glutamate. This interaction prevents the downstream signaling mediated by mGlu2, leading to a reduction in glutamate release and neurotransmission. By modulating the activity of mGlu2, MRS 3777 hemioxalate can be used to investigate the specific role of this receptor subtype in various physiological and pathological processes. Its mechanism of action at the molecular level involves interfering with the binding of glutamate to mGlu2 and altering the receptor′s conformation, ultimately influencing its signaling properties. In experimental applications, MRS 3777 hemioxalate serves as a functional significance of mGlu2 in cellular and synaptic processes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
5-Diethylaminomethyl-furan-3-carboxylic acid hydrochloride, 500 mg | sc-318647 | 500 mg | $284.00 |