Date published: 2025-12-5

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5-Deoxy-D-ribose (CAS 13039-75-3)

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CAS Number:
13039-75-3
Molecular Weight:
134.13
Molecular Formula:
C5H10O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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In the shikimate pathway, a pathway for the production of aromatic amino acids, 5-Deoxy-D-ribose serves as an intermediate molecule. It can be synthesized from D-ribose and shikimic acid. The enzyme ribose 5′-phosphate kinase catalyzes the biosynthesis of 5-Deoxy-D-ribose by converting ribose 5′-phosphate into 5-deoxy-D-ribose phosphate. This conversion requires ATP as an energy source, and its progress is hindered by phosphoribosyl pyrophosphate (PRPP). For the asymmetric synthesis of 5-Deoxy-D-ribose, researchers have successfully employed a chiral Lewis acid catalyst. The molecular structure of 5-Deoxy-D-ribose has been elucidated using NMR spectroscopy. While mammalian cells possess shikimate pathways, plants and bacteria lack this pathway.


5-Deoxy-D-ribose (CAS 13039-75-3) References

  1. N(delta)-(5-hydroxy-4,6-dimethylpyrimidine-2-yl)-l-ornithine, a novel methylglyoxal-arginine modification in beer.  |  Glomb, MA., et al. 2001. J Agric Food Chem. 49: 366-72. PMID: 11170600
  2. A Stereoselective Approach toward (-)-Lepadins A-C.  |  Li, X., et al. 2017. Org Lett. 19: 5372-5375. PMID: 28925708
  3. Cyanobacterial antimetabolite 7-deoxy-sedoheptulose blocks the shikimate pathway to inhibit the growth of prototrophic organisms.  |  Brilisauer, K., et al. 2019. Nat Commun. 10: 545. PMID: 30710081
  4. Computer Modelling and Synthesis of Deoxy and Monohydroxy Analogues of a Ribitylaminouracil Bacterial Metabolite that Potently Activates Human T Cells.  |  Ler, GJM., et al. 2019. Chemistry. 25: 15594-15608. PMID: 31529537
  5. Hybrid Chemoenzymatic Synthesis of C7 -Sugars for Molecular Evidence of in vivo Shikimate Pathway Inhibition.  |  Rath, P., et al. 2022. Chembiochem. 23: e202200241. PMID: 35508894

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

5-Deoxy-D-ribose, 500 mg

sc-284620
500 mg
$336.00

5-Deoxy-D-ribose, 1 g

sc-284620A
1 g
$520.00