5-Chloroisatin (CAS 17630-76-1)
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5-Chloroisatin is a chemical compound that functions as an inhibitor of certain enzymes involved in cellular processes. It acts by binding to the active site of the enzyme, thereby preventing its normal function and disrupting the biochemical pathways in which it participates. This disruption can lead to altered cellular signaling, gene expression, or metabolic processes, to study the specific functions of the inhibited enzyme. By interfering with the enzyme′s activity, 5-Chloroisatin can help its role in various cellular functions and pathways, contributing to a better understanding of the underlying biological mechanisms. 5-Chloroisatin′s mechanism of action involves specific interactions with the enzyme′s active site, leading to the inhibition of its catalytic activity and subsequent effects on cellular processes. 5-Chloroisatin serves as useful for investigating the functions and regulatory mechanisms of the targeted enzyme, providing insights into its role in cellular physiology and potential implications for various biological processes.
5-Chloroisatin (CAS 17630-76-1) References
- Polar [3 + 2] cycloaddition of ketones with electrophilically activated carbonyl ylides. Synthesis of spirocyclic dioxolane indolinones. | Bentabed-Ababsa, G., et al. 2008. Org Biomol Chem. 6: 3144-57. PMID: 18698474
- Synthesis of Schiff and Mannich bases of isatin derivatives with 4-amino-4,5-dihydro-1H-1,2,4-triazole-5-ones. | Bekircan, O. and Bektas, H. 2008. Molecules. 13: 2126-35. PMID: 18830145
- Synthesis of new functionalized thiazolo pyridine-fused and thiazolo pyridopyrimidine-fused spirooxindoles via one-pot reactions. | Nasri, S., et al. 2020. Heliyon. 6: e03687. PMID: 32258502
- Synthesis and Biological Evaluation of S-, O- and Se-Containing Dispirooxindoles. | Kukushkin, M., et al. 2021. Molecules. 26: PMID: 34946727
- Investigations on Anticancer Potentials by DNA Binding and Cytotoxicity Studies for Newly Synthesized and Characterized Imidazolidine and Thiazolidine-Based Isatin Derivatives. | Arshad, N., et al. 2022. Molecules. 27: PMID: 35056668
- [3+2]-Cycloaddition of azomethine ylides to 5-methylidene-3-aryl-2-сhalcogen-imidazolones: access to dispiro indolinone-pyrrolidine-imidazolones. | Kukushkin, ME., et al. 2022. R Soc Open Sci. 9: 211967. PMID: 35291328
- Guanidine functionalized core-shell structured magnetic cobalt-ferrite: an efficient nanocatalyst for sonochemical synthesis of spirooxindoles in water. | Dadaei, M. and Naeimi, H. 2021. RSC Adv. 11: 15360-15368. PMID: 35424043
- Synthesis of pyrazolo[5',1':2,3]imidazo[1,5-c]quinazolin-6(5H)-ones and molecular docking study of their affinity against the COVID-19 main protease. | Saeedi, S., et al. 2022. RSC Adv. 12: 19579-19589. PMID: 35919373
- Discovery of novel enasidenib analogues targeting inhibition of mutant isocitrate dehydrogenase 2 as antileukaemic agents. | Khalil, AF., et al. 2023. J Enzyme Inhib Med Chem. 38: 2157411. PMID: 36629449
- Synthesis, characterization, and anticancer activity of chitosan functionalized isatin based thiosemicarbazones, and their copper(II) complexes. | Adhikari, HS., et al. 2023. Carbohydr Res. 526: 108796. PMID: 36944301
- Effect of sunitinib derivatives on glioblastoma single-cell migration and 3D cell cultures. | Dabkeviciute, G., et al. 2023. Am J Cancer Res. 13: 1377-1386. PMID: 37168355
- Review on Isatin- A Remarkable Scaffold for Designing Potential Therapeutic Complexes and Its Macrocyclic Complexes with Transition Metals. | Bugalia, S., et al. 2023. J Inorg Organomet Polym Mater. 1-20. PMID: 37359385
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
5-Chloroisatin, 25 g | sc-254819 | 25 g | $34.00 |