Date published: 2026-4-25

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5-Chloro-1-pentyne (CAS 14267-92-6)

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Application:
5-Chloro-1-pentyne is an alkynyl substrate
CAS Number:
14267-92-6
Molecular Weight:
102.56
Molecular Formula:
C5H7Cl
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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An alkynyl substrate that is used with α-diazoesters in a copper-catalyzed synthesis of pyrazoles.(1)


5-Chloro-1-pentyne (CAS 14267-92-6) References

  1. Copper-promoted cycloaddition of diazocarbonyl compounds and acetylides.  |  Qi, X. and Ready, JM. 2007. Angew Chem Int Ed Engl. 46: 3242-4. PMID: 17378008
  2. Novel pleconaril derivatives: Influence of substituents in the isoxazole and phenyl rings on the antiviral activity against enteroviruses.  |  Egorova, A., et al. 2020. Eur J Med Chem. 188: 112007. PMID: 31881489
  3. The Evolution of Pleconaril: Modified O-Alkyl Linker Analogs Have Biological Activity towards Coxsackievirus B3 Nancy.  |  Volobueva, A., et al. 2020. Molecules. 25: PMID: 32188089
  4. Design of Clickable Ionic Liquid Monomers to Enhance Ionic Conductivity for Main-Chain 1,2,3-Triazolium-Based Poly(Ionic Liquid)s.  |  Hirai, R., et al. 2021. ACS Omega. 6: 10030-10038. PMID: 34056158
  5. A structure-specific small molecule inhibits a miRNA-200 family member precursor and reverses a type 2 diabetes phenotype.  |  Haniff, HS., et al. 2022. Cell Chem Biol. 29: 300-311.e10. PMID: 34320373
  6. Comparing C2=O and C2=S Barbiturates: Different Hydrogen-Bonding Patterns of Thiobarbiturates in Solution and the Solid State.  |  Li, C., et al. 2021. Int J Mol Sci. 22: PMID: 34884482
  7. One-pot synthesis of poly(ionic liquid)s with 1,2,3-triazolium-based backbones via clickable ionic liquid monomers.  |  Hirai, R., et al. 2020. RSC Adv. 10: 37743-37748. PMID: 35515169
  8. 18beta-glycyrrhetinic acid induces ROS-mediated apoptosis to ameliorate hepatic fibrosis by targeting PRDX1/2 in activated HSCs.  |  Zhang, Q., et al. 2022. J Pharm Anal. 12: 570-582. PMID: 36105163
  9. Comparison of Two Zinc Hydride Precatalysts for Selective Dehydrogenative Borylation of Terminal Alkynes: A Detailed Mechanistic Study.  |  Sahoo, RK., et al. 2023. ACS Omega. 8: 3452-3460. PMID: 36713704
  10. A Near-Infrared Fluorescent and Photoacoustic Probe for Visualizing Biothiols Dynamics in Tumor and Liver.  |  Ding, W., et al. 2023. Molecules. 28: PMID: 36903474
  11. LNL-Carbazole Pincer Ligand: More than the Sum of Its Parts.  |  Kleinhans, G., et al. 2023. Chem Rev. 123: 8781-8858. PMID: 37351619
  12. Copper-Metallized Porous N-Heterocyclic Carbene Ligand Polymer-Catalyzed Regio- and Stereoselective 1,2-Carboboration of Alkynes.  |  Jia, JS., et al. 2024. Adv Sci (Weinh). 11: e2308238. PMID: 38064182
  13. Development of a multi-targeted chemotherapeutic approach based on G-quadruplex stabilisation and carbonic anhydrase inhibition.  |  Nocentini, A., et al. 2024. J Enzyme Inhib Med Chem. 39: 2366236. PMID: 38905127

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

5-Chloro-1-pentyne, 5 g

sc-252259
5 g
$26.00