Date published: 2026-2-13

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1-Hydroxy-1,3-dihydrobenzo[c][1,2]oxaborole-6-carboxylic acid (CAS 1221343-14-1)

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Alternate Names:
5-Carboxybenzoboroxole
Application:
5-Carboxybenzoboroxole has reaction conditions which include but are not limited to hydrogenchloride in water.
CAS Number:
1221343-14-1
Purity:
≥95%
Molecular Weight:
177.95
Molecular Formula:
C8H7BO4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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1-Hydroxy-1,3-dihydrobenzo[c][1,2]oxaborole-6-carboxylic acid, also known as 1-Hydroxy-1,3-dihydro-2,1-benzoxaborole-6-carboxylic acid (HBCA), is a recently discovered carboxylic acid belonging to the family of boron-containing compounds. This novel acid has numerous potential applications in the fields of chemistry and biochemistry. Although the precise mechanism of action of 1-Hydroxy-1,3-dihydrobenzo[c][1,2]oxaborole-6-carboxylic acid is not entirely clear, it is postulated that it interacts with various molecules in the cell, such as proteins, causing changes in their function and structure. Consequently, these alterations can result in changes in the cell′s biochemical and physiological processes, ultimately affecting its behavior.


1-Hydroxy-1,3-dihydrobenzo[c][1,2]oxaborole-6-carboxylic acid (CAS 1221343-14-1) References

  1. Design, synthesis, and screening of a library of peptidyl bis(boroxoles) as oligosaccharide receptors in water: identification of a receptor for the tumor marker TF-antigen disaccharide.  |  Pal, A., et al. 2010. Angew Chem Int Ed Engl. 49: 1492-5. PMID: 20084659
  2. The binding of boronated peptides to low affinity mammalian saccharides.  |  Kowalczyk, W., et al. 2018. Biopolymers.. PMID: 29381187
  3. An enrichment method based on synergistic and reversible covalent interactions for large-scale analysis of glycoproteins.  |  Xiao, H., et al. 2018. Nat Commun. 9: 1692. PMID: 29703890
  4. Boron-Modified Defect-Rich Molybdenum Disulfide Nanosheets: Reducing Nonspecific Adsorption and Promoting a High Capacity for Isolation of Immunoglobulin G.  |  Wang, XM., et al. 2020. ACS Appl Mater Interfaces. 12: 43273-43280. PMID: 32852193

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1-Hydroxy-1,3-dihydrobenzo[c][1,2]oxaborole-6-carboxylic acid, 500 mg

sc-481921
500 mg
$297.00

1-Hydroxy-1,3-dihydrobenzo[c][1,2]oxaborole-6-carboxylic acid, 5 g

sc-481921A
5 g
$709.00