5-Bromouridine 5′-triphosphate sodium salt (CAS 161848-60-8)
See product citations (3)
QUICK LINKS
5-Bromouridine 5′-triphosphate sodium salt, also known as BrUTP, is a modified nucleotide that has gained significant popularity in scientific research for investigating RNA transcription and processing. This fluorescently-labeled nucleotide is capable of being integrated into RNA during transcription, facilitating the monitoring of RNA synthesis and processing within live cells. By substituting uridine triphosphate (UTP) during transcription, 5-Bromouridine 5′-triphosphate sodium salt becomes part of the RNA molecule. Its presence can then be identified using either fluorescent microscopy or flow cytometry. The fluorescence emitted by 5-Bromouridine 5′-triphosphate sodium salt enables researchers to effectively monitor the synthesis and processing of RNA in living cells.
5-Bromouridine 5′-triphosphate sodium salt (CAS 161848-60-8) References
- Protein expression redirects vesicular stomatitis virus RNA synthesis to cytoplasmic inclusions. | Heinrich, BS., et al. 2010. PLoS Pathog. 6: e1000958. PMID: 20585632
- Induction of stress granule-like structures in vesicular stomatitis virus-infected cells. | Dinh, PX., et al. 2013. J Virol. 87: 372-83. PMID: 23077311
- Nucleolus-like bodies of fully-grown mouse oocytes contain key nucleolar proteins but are impoverished for rRNA. | Shishova, KV., et al. 2015. Dev Biol. 397: 267-81. PMID: 25481757
- Trigger loop folding determines transcription rate of Escherichia coli's RNA polymerase. | Mejia, YX., et al. 2015. Proc Natl Acad Sci U S A. 112: 743-8. PMID: 25552559
- Embryonic Poly(A)-Binding Protein Is Required During Early Stages of Mouse Oocyte Development for Chromatin Organization, Transcriptional Silencing, and Meiotic Competence. | Lowther, KM. and Mehlmann, LM. 2015. Biol Reprod. 93: 43. PMID: 26134869
- High-resolution microscopy of active ribosomal genes and key members of the rRNA processing machinery inside nucleolus-like bodies of fully-grown mouse oocytes. | Shishova, KV., et al. 2015. Exp Cell Res. 337: 208-18. PMID: 26226217
- UV Irradiation Induces a Non-coding RNA that Functionally Opposes the Protein Encoded by the Same Gene. | Williamson, L., et al. 2017. Cell. 168: 843-855.e13. PMID: 28215706
- Nipah virus induces two inclusion body populations: Identification of novel inclusions at the plasma membrane. | Ringel, M., et al. 2019. PLoS Pathog. 15: e1007733. PMID: 31034506
- Targeting Spt5-Pol II by Small-Molecule Inhibitors Uncouples Distinct Activities and Reveals Additional Regulatory Roles. | Bahat, A., et al. 2019. Mol Cell. 76: 617-631.e4. PMID: 31564557
- Conserved Rotavirus NSP5 and VP2 Domains Interact and Affect Viroplasm. | Buttafuoco, A., et al. 2020. J Virol. 94: PMID: 31915278
- MDC1 maintains active elongation complexes of RNA polymerase II. | Pappas, G., et al. 2023. Cell Rep. 42: 111979. PMID: 36640322
- Combined Detection of Newly Synthesized RNA and Nuclear Proteins at the Ultrastructural Level: a Modification of the Protocol for Immunoelectron Microscopy | , et al. (2018). Cell and Tissue Biology. volume 12,: pages 517–522.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
5-Bromouridine 5′-triphosphate sodium salt, 5 mg | sc-214314 | 5 mg | $109.00 | |||
5-Bromouridine 5′-triphosphate sodium salt, 10 mg | sc-214314A | 10 mg | $161.00 | |||
5-Bromouridine 5′-triphosphate sodium salt, 50 mg | sc-214314B | 50 mg | $567.00 |