Date published: 2026-4-25

1-800-457-3801

SCBT Portrait Logo
Seach Input

5-Bromoindole-3-acetic acid (CAS 40432-84-6)

0.0(0)
Write a reviewAsk a question

CAS Number:
40432-84-6
Molecular Weight:
254.08
Molecular Formula:
C10H8BrNO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

5-Bromoindole-3-acetic acid is a brominated indole derivative, which is a type of aromatic hydrocarbon that is found in many naturally occurring compounds. 5-Bromoindole-3-acetic acid is a versatile compound that can be used as a starting material in the synthesis of other compounds, as a reagent for chemical reactions, and as a tool for studying the structure and function of proteins. Research indicates that it can suppress the functions of enzymes like cyclooxygenase-2 and 5-lipoxygenase, which play roles in inflammation and pain, while also influencing the activity of receptors such as the serotonin 5-HT2A receptor that regulates mood and behavior.


5-Bromoindole-3-acetic acid (CAS 40432-84-6) References

  1. Cytotoxic bromoindole derivatives and terpenes from the Philippine marine sponge Smenospongia sp.  |  Tasdemir, D., et al. 2002. Z Naturforsch C J Biosci. 57: 914-22. PMID: 12440734
  2. Analysis of the horseradish peroxidase/indole-3-acetic acid combination in a three-dimensional tumor model.  |  Tupper, J., et al. 2004. Cancer Gene Ther. 11: 508-13. PMID: 15143345
  3. From bench to bedside for gene-directed enzyme prodrug therapy of cancer.  |  Dachs, GU., et al. 2005. Anticancer Drugs. 16: 349-59. PMID: 15746571
  4. Structure-activity relationship analysis of the peptide deformylase inhibitor 5-bromo-1H-indole-3-acetohydroxamic acid.  |  Petit, S., et al. 2009. ChemMedChem. 4: 261-75. PMID: 19053131
  5. Purification of a recombinant plant peroxidase produced in Pichia pastoris by a simple 2-step strategy.  |  Spadiut, O., et al. 2012. Protein Expr Purif. 86: 89-97. PMID: 23026679
  6. Defining the selectivity of processes along the auxin response chain: a study using auxin analogues.  |  Simon, S., et al. 2013. New Phytol. 200: 1034-48. PMID: 23914741
  7. Restoration of NBD1 thermal stability is necessary and sufficient to correct ∆F508 CFTR folding and assembly.  |  He, L., et al. 2015. J Mol Biol. 427: 106-20. PMID: 25083918
  8. Identification of structure-activity relationships from screening a structurally compact DNA-encoded chemical library.  |  Franzini, RM., et al. 2015. Angew Chem Int Ed Engl. 54: 3927-31. PMID: 25650139
  9. Fibroin particle-supported cationic lipid layers for highly efficient intracellular protein delivery.  |  Kim, WJ., et al. 2017. Biomaterials. 122: 154-162. PMID: 28119155
  10. Immobilization of horseradish peroxidase into cubic mesoporous silicate, SBA-16 with high activity and enhanced stability.  |  El-Nahass, MN., et al. 2018. Int J Biol Macromol. 116: 1304-1309. PMID: 29738866
  11. Spermine Derivatives of Indole-3-carboxylic Acid, Indole-3-acetic Acid and Indole-3-acrylic Acid as Gram-Negative Antibiotic Adjuvants.  |  Cadelis, MM., et al. 2021. ChemMedChem. 16: 513-523. PMID: 33090655
  12. Transcriptomic evaluation on methyl bromide-induced phytotoxicity in Arabidopsis thaliana and its mode of phytotoxic action via the occurrence of reactive oxygen species and uneven distribution of auxin hormones.  |  Kim, K., et al. 2021. J Hazard Mater. 419: 126419. PMID: 34171674
  13. Nanomechanics combined with HDX reveals allosteric drug binding sites of CFTR NBD1.  |  Padányi, R., et al. 2022. Comput Struct Biotechnol J. 20: 2587-2599. PMID: 35685375
  14. Hydroxyindole-O-methyltransferase. V. Effects of substituents on hydrolysis of N-acyltryptamines in rats.  |  Ho, BT., et al. 1971. J Pharm Sci. 60: 634-5. PMID: 5166867
  15. Solid-phase synthesis of a focused library of trypanothione reductase inhibitors  |  Stefania De Luca, Saraj Ulhaq, Mark J. Dixon, Jonathan Essex, Mark Bradley. 2003. Tetrahedron Letters. 44: 3195-3197.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

5-Bromoindole-3-acetic acid, 1 g

sc-254793
1 g
$160.00