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5-Bromo-4-chloro-3-indolyl-α-L-fucopyranoside (CAS 171869-92-4)

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Alternate Names:
X-α-L-fucopyranoside; X-α-L-Fucoside
Application:
CAS Number:
171869-92-4
Molecular Weight:
392.64
Molecular Formula:
C14H15BrClNO5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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5-Bromo-4-chloro-3-indolyl-α-L-fucopyranoside is employed as a chromogenic substrate for FUCA (alpha-L-Fucosidase), producing a blue precipitate. 5-Bromo-4-chloro-3-indolyl-α-L-fucopyranoside (5-BCI-a-L-Fuc) is a water-soluble synthetic compound derived from fucose, a naturally occurring sugar. It possesses distinct structural and biochemical characteristics, making it highly valuable for scientific research purposes.


5-Bromo-4-chloro-3-indolyl-α-L-fucopyranoside (CAS 171869-92-4) References

  1. Directed evolution of the alpha-L-fucosidase from Thermotoga maritima into an alpha-L-transfucosidase.  |  Osanjo, G., et al. 2007. Biochemistry. 46: 1022-33. PMID: 17240986
  2. α-Fucosidase as a novel convenient biomarker for cellular senescence.  |  Hildebrand, DG., et al. 2013. Cell Cycle. 12: 1922-7. PMID: 23673343
  3. α-L-fucosidase from Paenibacillus thiaminolyticus: its hydrolytic and transglycosylation abilities.  |  Benesová, E., et al. 2013. Glycobiology. 23: 1052-65. PMID: 23723440
  4. Rapid fucosylation of intestinal epithelium sustains host-commensal symbiosis in sickness.  |  Pickard, JM., et al. 2014. Nature. 514: 638-41. PMID: 25274297
  5. Alpha-L-fucosidase isoenzyme iso2 from Paenibacillus thiaminolyticus.  |  Benešová, E., et al. 2015. BMC Biotechnol. 15: 36. PMID: 26013545
  6. Novel α-L-Fucosidases from a Soil Metagenome for Production of Fucosylated Human Milk Oligosaccharides.  |  Lezyk, M., et al. 2016. PLoS One. 11: e0147438. PMID: 26800369
  7. A multi-substrate approach for functional metagenomics-based screening for (hemi)cellulases in two wheat straw-degrading microbial consortia unveils novel thermoalkaliphilic enzymes.  |  Maruthamuthu, M., et al. 2016. BMC Genomics. 17: 86. PMID: 26822785
  8. Simple Detection Methods for Senescent Cells: Opportunities and Challenges.  |  Faragher, RGA. 2021. Front Aging. 2: 686382. PMID: 35822046

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

5-Bromo-4-chloro-3-indolyl-α-L-fucopyranoside, 25 mg

sc-284558
25 mg
$222.00

5-Bromo-4-chloro-3-indolyl-α-L-fucopyranoside, 50 mg

sc-284558A
50 mg
$362.00