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5-Aminoquinoline (CAS 611-34-7)

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Application:
5-Aminoquinoline is an intermediate in the preparation of P2X7 antagonists
CAS Number:
611-34-7
Molecular Weight:
144.17
Molecular Formula:
C9H8N2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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5-Aminoquinoline is an intermediate in the preparation of P2X7 antagonists.


5-Aminoquinoline (CAS 611-34-7) References

  1. [3H]A-804598 ([3H]2-cyano-1-[(1S)-1-phenylethyl]-3-quinolin-5-ylguanidine) is a novel, potent, and selective antagonist radioligand for P2X7 receptors.  |  Donnelly-Roberts, DL., et al. 2009. Neuropharmacology. 56: 223-9. PMID: 18602931
  2. Discovery and biological evaluation of novel cyanoguanidine P2X(7) antagonists with analgesic activity in a rat model of neuropathic pain.  |  Perez-Medrano, A., et al. 2009. J Med Chem. 52: 3366-76. PMID: 19397270
  3. Quantum chemical and spectroscopic investigations of 5-aminoquinoline.  |  Arjunan, V., et al. 2009. Spectrochim Acta A Mol Biomol Spectrosc. 74: 1215-23. PMID: 19854675
  4. Photochemistry of 5-aminoquinoline in protic and aprotic solvents.  |  Bridhkoti, JP., et al. 2011. Spectrochim Acta A Mol Biomol Spectrosc. 79: 412-7. PMID: 21501968
  5. The two faces of aldehyde oxidase: Oxidative and reductive transformations of 5-nitroquinoline.  |  Paragas, EM., et al. 2017. Biochem Pharmacol. 145: 210-217. PMID: 28888950
  6. Solvation and hydrogen bonding aided efficient non-radiative deactivation of polar excited state of 5-aminoquinoline.  |  Singh, AK., et al. 2018. Phys Chem Chem Phys. 20: 22320-22330. PMID: 30124696
  7. Dynamics of Preferential Solvation of 5-Aminoquinoline in Hexane-Alcohol Solvent Mixtures.  |  Das, S., et al. 2019. J Phys Chem B. 123: 10267-10274. PMID: 31689106
  8. The Role of Hydrogen Bonding in the Preferential Solvation of 5-Aminoquinoline in Binary Solvent Mixtures.  |  Das, S., et al. 2021. J Phys Chem B. 125: 12763-12773. PMID: 34709811
  9. 3-aminoquinoline: a turn-on fluorescent probe for preferential solvation in binary solvent mixtures.  |  Das, S., et al. 2022. Methods Appl Fluoresc. 10: PMID: 35697038
  10. Metabolism of 5-aminoquinoline with liver cytosol enzyme.  |  Banoo, R. and Matheison, DW. 1993. Indian J Biochem Biophys. 30: 229-33. PMID: 8276426

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

5-Aminoquinoline, 5 g

sc-217139
5 g
$330.00