Date published: 2026-4-25

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5-Amino-4,6-dichloropyrimidine (CAS 5413-85-4)

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Application:
5-Amino-4,6-dichloropyrimidine is an intermediate in the production of a variety of biological inhibitors
CAS Number:
5413-85-4
Molecular Weight:
163.99
Molecular Formula:
C4H3Cl2N3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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5-Amino-4,6-dichloropyrimidine is an intermediate in the production of a lot of biological inhibitors.


5-Amino-4,6-dichloropyrimidine (CAS 5413-85-4) References

  1. Identification and synthesis of 2,7-diamino-thiazolo[5,4-d]pyrimidine derivatives as TRPV1 antagonists.  |  Lebsack, AD., et al. 2009. Bioorg Med Chem Lett. 19: 40-6. PMID: 19038548
  2. Discovery of 1-[9-(4-chlorophenyl)-8-(2-chlorophenyl)-9H-purin-6-yl]-4-ethylaminopiperidine-4-carboxylic acid amide hydrochloride (CP-945,598), a novel, potent, and selective cannabinoid type 1 receptor antagonist.  |  Griffith, DA., et al. 2009. J Med Chem. 52: 234-7. PMID: 19102698
  3. 8-Bromo-9-alkyl adenine derivatives as tools for developing new adenosine A2A and A2B receptors ligands.  |  Lambertucci, C., et al. 2009. Bioorg Med Chem. 17: 2812-22. PMID: 19282184
  4. Syntheses of isoxazoline-carbocyclic nucleosides and their antiviral evaluation: a standard protocol.  |  Quadrelli, P., et al. 2014. ScientificWorldJournal. 2014: 492178. PMID: 25544956
  5. Alicyclic β- and γ-Amino Acids: Useful Scaffolds for the Stereocontrolled Access to Amino Acid-Based Carbocyclic Nucleoside Analogs.  |  Remete, AM. and Kiss, L. 2019. Molecules. 24: PMID: 30609864
  6. Synthesis of New Indanyl Nucleoside Analogues and their Biological Evaluation on Hepatitis C Virus (HCV) Replicon.  |  Gómez, ME., et al. 2019. Molecules. 24: PMID: 30862130
  7. Identification of 6'-β-fluoro-homoaristeromycin as a potent inhibitor of chikungunya virus replication.  |  Shin, YS., et al. 2020. Eur J Med Chem. 187: 111956. PMID: 31841728
  8. Antiproliferative Activity of (-)-Isopulegol-based 1,3-Oxazine, 1,3-Thiazine and 2,4-Diaminopyrimidine Derivatives.  |  Bamou, FZ., et al. 2022. ChemistryOpen. 11: e202200169. PMID: 36200514
  9. Inhibition of the RNA-Dependent RNA-Polymerase from SARS-CoV-2 by 6-Chloropurine Isoxazoline-Carbocyclic Monophosphate Nucleotides.  |  Leusciatti, M., et al. 2023. ACS Omega. 8: 36311-36320. PMID: 37810686
  10. Exploration of novel 6,8,9-trisubstituted purine analogues: synthesis, in vitro biological evaluation, and their effect on human cancer cells.  |  Polat, MF., et al. 2024. Turk J Chem. 48: 108-115. PMID: 38544902

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

5-Amino-4,6-dichloropyrimidine, 5 g

sc-217130
5 g
$330.00