5-Amino-3-phenyl-1,2,4-thiadiazole (CAS 17467-15-1)

5-Amino-3-phenyl-1,2,4-thiadiazole is a significant organic compound extensively employed in diverse scientific research domains. 5-Amino-3-phenyl-1,2,4-thiadiazole has found extensive use in scientific research applications due to its remarkable reactivity and stability. It has been employed in synthesizing various heterocyclic compounds, including derivatives of 1,2,4-triazol-3-yl-phenyl and 2-aryl-5-aminothiadiazoles. Additionally, the compound has been utilized in synthesizing organic compounds such as derivatives of 5-amino-1,2,4-thiadiazole-3-phenyl and 5-amino-1,2,4-thiadiazol-3-phenyl-3-methyl. It has further found application in the synthesis of polymers like poly(5-Amino-3-phenyl-1,2,4-thiadiazole). Furthermore, 5-Amino-3-phenyl-1,2,4-thiadiazole acts as an inhibitor of cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX). Additionally, the compound inhibits the release of pro-inflammatory cytokines such as tumor necrosis factor-alpha (TNF-α) and interleukin-1β (IL-1β).