Molecular structure of 5-Amino-1,3,4-thiadiazole-2-thiol, CAS Number: 2349-67-9
5-Amino-1,3,4-thiadiazole-2-thiol (CAS 2349-67-9)
Alternate Names:
2-Amino-5-mercapto-1,3,4-thiadiazole
Application:
5-Amino-1,3,4-thiadiazole-2-thiol is a substituted thiadiazole used to prepare various amines
CAS Number:
2349-67-9
Molecular Weight:
133.20
Molecular Formula:
C2H3N3S2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
5-Amino-1,3,4-thiadiazole-2-thiol is a compound that functions as a nucleophilic reagent in organic synthesis. It acts as a sulfur-containing building block in the formation of various heterocyclic compounds. The thiol group in the molecule can participate in nucleophilic substitution reactions, allowing for the introduction of the 5-amino-1,3,4-thiadiazole moiety into target molecules. 5-Amino-1,3,4-Thiadiazole-2-Thiol′s mechanism of action involves its ability to react with electrophiles, forming new carbon-sulfur bonds and contributing to the structural diversity of organic compounds. The amino group can serve as a site for further functionalization, enabling the modification of the compound for specific research purposes.
5-Amino-1,3,4-thiadiazole-2-thiol (CAS 2349-67-9) References
- Coordination mode of pentadentate ligand derivative of 5-amino-1,3,4-thiadiazole-2-thiol with nickel(II) and copper(II) metal ions: synthesis, spectroscopic characterization, molecular modeling and fungicidal study. | Chandra, S., et al. 2015. Spectrochim Acta A Mol Biomol Spectrosc. 136 Pt B: 672-81. PMID: 25448967
- Capped cadmium sulfide quantum dots with a new ionic liquid as a fluorescent probe for sensitive detection of florfenicol in meat samples. | Sadeghi, S. and Olieaei, S. 2019. Spectrochim Acta A Mol Biomol Spectrosc. 223: 117349. PMID: 31319275
- Allosteric kidney-type glutaminase (GLS) inhibitors with a mercaptoethyl linker. | Duvall, B., et al. 2020. Bioorg Med Chem. 28: 115698. PMID: 33069080
- Anti-biofilm Fe3O4@C18-[1,3,4]thiadiazolo[3,2-a]pyrimidin-4-ium-2-thiolate Derivative Core-shell Nanocoatings. | Olar, R., et al. 2020. Materials (Basel). 13: PMID: 33080907
- In Vitro Cytotoxicity and Apoptosis Inducing Evaluation of Novel Halogenated Isatin Derivatives. | Adibi, H., et al. 2022. Anticancer Agents Med Chem. 22: 2439-2447. PMID: 35043767
- Quantitative determination of uric acid using paper-based biosensor modified with graphene oxide and 5-amino-1,3,4-thiadiazole-2-thiol. | Chang, YJ., et al. 2022. SLAS Technol. 27: 54-62. PMID: 35058204
- Chirality-influenced antibacterial activity of methylthiazole- and thiadiazole-based supramolecular biocompatible hydrogels. | Baddi, S., et al. 2022. Acta Biomater. 141: 59-69. PMID: 35063710
- 1,3,4-Thiadiazol derivative functionalized-Fe3O4@SiO2 nanocomposites as a fluorescent probe for detection of Hg2+ in water samples. | Mir, N., et al. 2018. RSC Adv. 8: 21745-21753. PMID: 35541718
- Silver(I) complexes bearing heterocyclic thioamide ligands with NH2 and CF3 substituents: effect of ligand group substitution on antibacterial and anticancer properties. | Varna, D., et al. 2022. Dalton Trans. 51: 9412-9431. PMID: 35674362
- Repurposing Halicin as a potent covalent inhibitor for the SARS-CoV-2 main protease. | Yang, KS., et al. 2022. Curr Res Chem Biol. 2: 100025. PMID: 35815070
- Design, Synthesis, and Anti-Inflammatory Activity of Some Coumarin Schiff Base Derivatives: In silico and in vitro Study. | Hamid, SJ. and Salih, T. 2022. Drug Des Devel Ther. 16: 2275-2288. PMID: 35860526
- New thiadiazole modified chitosan derivative to control the growth of human pathogenic microbes and cancer cell lines. | Ibrahim, AG., et al. 2022. Sci Rep. 12: 21423. PMID: 36503959
- Design, synthesis, and biological investigation of oxadiazolyl, thiadiazolyl, and pyrimidinyl linked antipyrine derivatives as potential non-acidic anti-inflammatory agents. | Al-Sanea, MM., et al. 2023. J Enzyme Inhib Med Chem. 38: 2162511. PMID: 36633257
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
5-Amino-1,3,4-thiadiazole-2-thiol, 25 g | sc-226902 | 25 g | $40.00 | |||
5-Amino-1,3,4-thiadiazole-2-thiol, 100 g | sc-226902A | 100 g | $100.00 |