Molecular structure of 5,7-Dichlorokynurenic acid sodium salt, CAS Number: 1184986-70-6
5,7-Dichlorokynurenic acid sodium salt (CAS 1184986-70-6)
Alternate Names:
5,7-Dichloro-4-hydroxyquinoline-2-carboxylic acid sodium salt
Application:
5,7-Dichlorokynurenic acid sodium salt is a potent antagonist at the glycine site of the NMDA receptor
CAS Number:
1184986-70-6
Molecular Weight:
280.04
Molecular Formula:
C10H4Cl2NO3•Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
5,7-Dichlorokynurenic acid sodium salt is that sodium salt form of 5,7-Dichlorokynurenic acid (sc-200440). It acts as a potent antagonist at the glycine site of the NMDA receptor (Ki = 79 nM vs. [3H]-glycine). The synthetic compound, 5,7-Dichlorokynurenic acid sodium salt, serves as a structural analog of the neurotransmitter glutamate. It can be used to investigate the impact of glutamate on the nervous system.
5,7-Dichlorokynurenic acid sodium salt (CAS 1184986-70-6) References
- Activity of 5,7-dichlorokynurenic acid, a potent antagonist at the N-methyl-D-aspartate receptor-associated glycine binding site. | Baron, BM., et al. 1990. Mol Pharmacol. 38: 554-61. PMID: 2172769
- GluN3A excitatory glycine receptors control adult cortical and amygdalar circuits. | Bossi, S., et al. 2022. Neuron. 110: 2438-2454.e8. PMID: 35700736
Inhibitor of:
NMDA.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
5,7-Dichlorokynurenic acid sodium salt, 10 mg | sc-291018 | 10 mg | $99.00 | |||
5,7-Dichlorokynurenic acid sodium salt, 50 mg | sc-291018A | 50 mg | $409.00 |