Date published: 2026-4-25

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5(6)-TAMRA, SE (CAS 246256-50-8)

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Alternate Names:
5-(and-6)-Carboxytetramethylrhodamine, succinimidyl ester
CAS Number:
246256-50-8
Molecular Weight:
527.53
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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5(6)-TAMRA, SE is an amine-reactive fluorescent probe. It has been used in double site-directed peptide modification to label proteinase substrates for use in FRET assays. It quenches lucifer yellow CH fluorescence by greater than 90% in uncleaved proteinase substrates, which allows for the detection of enzyme-cleaved substrates by an increase in fluorescence intensity. It has also been used in the synthesis of fluorescent derivatives of a variety of compounds, including the antibiotic ampicillin (sc-210812), nucleotide diphosphate uridine-5′-diphosphate, and the progesterone receptor antagonist RU486 (mifepristone sc-203134).


5(6)-TAMRA, SE (CAS 246256-50-8) References

  1. Design and synthesis of new acid cleavable linkers for DNA sequencing by synthesis.  |  Jiang, M., et al. 2014. Nucleosides Nucleotides Nucleic Acids. 33: 774-85. PMID: 25372993
  2. Labelling peptides with fluorescent probes for incorporation into degradable polymers.  |  Brunner, A., et al. 1998. Eur J Pharm Biopharm. 45: 265-73. PMID: 9653631

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

5(6)-TAMRA, SE, 25 mg

sc-495645
25 mg
$136.00