5,6-Dihydro-benzo[c]acridine-7-carboxylic acid (CAS 83-93-2)

LY 487379 hydrochloride is a selective and potent inhibitor of the dopamine transporter (DAT). It functions by binding to the DAT and preventing the reuptake of dopamine from the synaptic cleft into the presynaptic neuron. This leads to an increase in dopamine levels in the synaptic cleft, ultimately enhancing dopaminergic neurotransmission. LY 487379 hydrochloride′s mechanism of action involves blocking the transport of dopamine back into the presynaptic neuron, thereby prolonging the action of dopamine at the postsynaptic receptor. This mechanism of action is for studying the role of dopamine in various physiological and pathological processes, as it allows to manipulate dopamine levels in the brain. LY 487379 hydrochloride′s ability to target the dopamine transporter may be useful for investigating the role of dopamine in reward, addiction, and motor control, among other functions. Its precise mechanism of action at the molecular level provides a means to modulate dopaminergic neurotransmission in experimental applications.