Molecular structure of 5,6-dehydro Arachidonic Acid, CAS Number: 58688-54-3
5,6-dehydro Arachidonic Acid (CAS 58688-54-3)
Application:
5,6-dehydro Arachidonic Acid is a 5-LO inhibitor
CAS Number:
58688-54-3
Molecular Weight:
302.46
Molecular Formula:
C20H30O2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
5,6-dehydro Arachidonic Acid is an analog of arachidonic acid with an acetylene in the 5,6 position and an inhibitor of 5-LO (Ki = 15 μM in rat basophilic leukemia cells, IC50 = 10 μM In guinea pig leukocytes).
5,6-dehydro Arachidonic Acid (CAS 58688-54-3) References
- Platelet-induced growth of human fibroblasts is associated with an increased expression of 5-lipoxygenase. | Berg, C., et al. 2006. Thromb Haemost. 96: 652-9. PMID: 17080223
- Blockade of TRPM7 channel activity and cell death by inhibitors of 5-lipoxygenase. | Chen, HC., et al. 2010. PLoS One. 5: e11161. PMID: 20567598
- Conversion of 5-hydroperoxyeicosatetraenoic acid into leukotriene B4 by rat hepatocytes: a novel cellular source for leukotriene B4. | Gut, J., et al. 1988. Mol Pharmacol. 34: 256-64. PMID: 2843745
- Inhibition of leukotriene biosynthesis by acetylenic analogs. | Sok, DE., et al. 1982. Biochem Biophys Res Commun. 107: 101-8. PMID: 6127073
- Inhibition of arachidonate lipoxygenase activities by 2-(3,4-dihydroxyphenyl)ethanol, a phenolic compound from olives. | Kohyama, N., et al. 1997. Biosci Biotechnol Biochem. 61: 347-50. PMID: 9058975
Inhibitor of:
5-LO.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
5,6-dehydro Arachidonic Acid, 25 µg | sc-205145 | 25 µg | $160.00 | |||
5,6-dehydro Arachidonic Acid, 50 µg | sc-205145A | 50 µg | $304.00 |