Date published: 2025-11-15

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5,5′-Dithiobis(1-phenyl-1H-tetrazole) (CAS 5117-07-7)

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Alternate Names:
1,1-Diphenyl-bistetrazole-5,5-disulfide
Application:
CAS Number:
5117-07-7
Purity:
95%
Molecular Weight:
354.41
Molecular Formula:
C14H10N8S2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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5,5′-Dithiobis(1-phenyl-1H-tetrazole) is an organic disulphide. It may be used in the preparation of 5-(5-nitropyridin-2-yldithio)-1-phenyl-1H-tetrazole. It may act to interact with specific enzymes, such as cytochrome P450 and cytochrome b5, and inhibit their activity. In addition, 5,5′-Dithiobis(1-phenyl-1H-tetrazole) has been found to interact with other proteins, such as phospholipase A2, and inhibit their activity as well.


5,5′-Dithiobis(1-phenyl-1H-tetrazole) (CAS 5117-07-7) References

  1. Effects of glucocorticoid on brain acetylcholinesterase of developing chick embryos.  |  Yamate, S., et al. 2010. J Obstet Gynaecol Res. 36: 11-8. PMID: 20178522
  2. N,N'-Dithiobisphthalimide, a disulfide aromatic compound, is a potent spermicide agent in humans.  |  Florez, M., et al. 2011. Syst Biol Reprod Med. 57: 309-17. PMID: 21942567
  3. Mechanistic and preparative studies of radical chain homolytic substitution reactions of N-heterocyclic carbene boranes and disulfides.  |  Pan, X., et al. 2013. J Am Chem Soc. 135: 10484-91. PMID: 23718209
  4. Metal-Free Preparation of Cycloalkyl Aryl Sulfides via Di-tert-butyl Peroxide-Promoted Oxidative C(sp3)[BOND]H Bond Thiolation of Cycloalkanes.  |  Zhao, J., et al. 2014. Adv Synth Catal. 356: 2719-2724. PMID: 25505857
  5. Total Synthesis of Mycalolides A and B through Olefin Metathesis.  |  Kita, M., et al. 2015. Angew Chem Int Ed Engl. 54: 14174-8. PMID: 26450520
  6. Synthesis and Biological Activities of Aplyronine A Analogues toward the Development of Antitumor Protein-Protein Interaction Inducers between Actin and Tubulin: Conjugation of the C1-C9 Macrolactone Part and the C24-C34 Side Chain.  |  Futaki, K., et al. 2019. ACS Omega. 4: 8598-8613. PMID: 31459949

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

5,5′-Dithiobis(1-phenyl-1H-tetrazole), 5 g

sc-233458
5 g
$194.00