5,5′-Difluoro BAPTA (AM) (CAS 156027-00-8)
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5,5i difluoro Bapta(AM) is a cell-permeable non-fluorescent Ca2+ indicator. BAPTA and its derivatives are calcium chelators that are commonly used to form calcium buffers with well-defined calcium concentrations. BAPTA chelators provide an important means to study the roles of calcium in cells. The AM ester forms of the BAPTA chelators allow for control of the cytosolic calcium concentrations when injected into or incubated with cells. Key advantages of these calcium chelators include relative insensitivity toward intracellular pH change and fast release of calcium. Additional BAPTA chelators available: BAPTA, Free Acid (sc-201508) BAPTA tetrapotassium salt (sc-202076) BAPTA/AM (sc-202488) BAPTA-APM (sc-206966) BAPTA-TMFM (sc-212043) 5,5i difluoro Bapta(K+ Salt) (sc-217248) Bapta-FF (AM) (sc-217696) BAPTA, Tetrasodium Salt (sc-278716)
5,5′-Difluoro BAPTA (AM) (CAS 156027-00-8) References
- Novel action of BAPTA series chelators on intrinsic K+ currents in rat hippocampal neurones. | Lancaster, B. and Batchelor, AM. 2000. J Physiol. 522 Pt 2: 231-46. PMID: 10639100
- Calcium regulates the association between mitochondria and a smooth subdomain of the endoplasmic reticulum. | Wang, HJ., et al. 2000. J Cell Biol. 150: 1489-98. PMID: 10995452
- Rhod-2 based measurements of intracellular calcium in the perfused mouse heart: cellular and subcellular localization and response to positive inotropy. | MacGowan, GA., et al. 2001. J Biomed Opt. 6: 23-30. PMID: 11178577
- BAPTA/AM, an intracellular calcium chelator, induces delayed necrosis by lipoxygenase-mediated free radicals in mouse cortical cultures. | Wie, MB., et al. 2001. Prog Neuropsychopharmacol Biol Psychiatry. 25: 1641-59. PMID: 11642660
- Comparison of human recombinant adenosine A2B receptor function assessed by Fluo-3-AM fluorometry and microphysiometry. | Patel, H., et al. 2003. Br J Pharmacol. 138: 671-7. PMID: 12598421
- Synthesis, structure-activity relationship and in vitro evaluation of coelenterazine and coelenteramine derivatives as inhibitors of lipid peroxidation. | Burton, M., et al. 2003. Free Radic Res. 37: 145-58. PMID: 12653203
- Cytosolic calcium in the ischemic rabbit heart: assessment by pH- and temperature-adjusted rhod-2 spectrofluorometry. | Stamm, C., et al. 2003. Cardiovasc Res. 59: 695-704. PMID: 14499871
- An Excel-based model of Ca2+ diffusion and fura 2 measurements in a spherical cell. | McHugh, JM. and Kenyon, JL. 2004. Am J Physiol Cell Physiol. 286: C342-8. PMID: 14512292
- Ratiometric intracellular calcium imaging in the isolated beating rat heart using indo-1 fluorescence. | Eerbeek, O., et al. 2004. J Appl Physiol (1985). 97: 2042-50. PMID: 15208283
- Epidermal keratinocyte polarity and motility require Ca²⁺ influx through TRPV1. | Graham, DM., et al. 2013. J Cell Sci. 126: 4602-13. PMID: 23943873
- Intracellular BAPTA directly inhibits PFKFB3, thereby impeding mTORC1-driven Mcl-1 translation and killing MCL-1-addicted cancer cells. | Sneyers, F., et al. 2023. Cell Death Dis. 14: 600. PMID: 37684238
- Impact of cytoplasmic calcium buffering on the spatial and temporal characteristics of intercellular calcium signals in astrocytes. | Wang, Z., et al. 1997. J Neurosci. 17: 7359-71. PMID: 9295382
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
5,5'-Difluoro BAPTA (AM), 25 mg | sc-217247 | 25 mg | $374.00 |