Date published: 2025-11-7

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5,5′-Dibromo-BAPTA (CAS 111248-72-7)

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Alternate Names:
1,2-Bis(2-amino-5-bromophenoxy)ethane-N,N,N′,N′-tetraacetic acid
Application:
5,5′-Dibromo-BAPTA is a calcium buffer
CAS Number:
111248-72-7
Purity:
≥94%
Molecular Weight:
634.23
Molecular Formula:
C22H22Br2N2O10
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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5,5′-Dibromo-BAPTA functions as a chelating agent by effectively binding with metal ions, resulting in the formation of a complex. This complex has the ability to attach to various molecules, including proteins and enzymes, enabling the detection of specific molecules within a given sample. Moreover, 5,5′-Dibromo-BAPTA serves the purpose of segregating and extracting molecules from a sample by creating a barrier through the formation of the complex.


5,5′-Dibromo-BAPTA (CAS 111248-72-7) References

  1. Construction of a derivative of Agrobacterium tumefaciens C58 that does not mutate to tetracycline resistance.  |  Luo, ZQ., et al. 2001. Mol Plant Microbe Interact. 14: 98-103. PMID: 11194879
  2. Cardiomyopathic tropomyosin mutations that increase thin filament Ca2+ sensitivity and tropomyosin N-domain flexibility.  |  Heller, MJ., et al. 2003. J Biol Chem. 278: 41742-8. PMID: 12900417
  3. Functional integration of embryonic stem cell-derived neurons in vivo.  |  Wernig, M., et al. 2004. J Neurosci. 24: 5258-68. PMID: 15175396
  4. Extracellular ATP induces the accumulation of superoxide via NADPH oxidases in Arabidopsis.  |  Song, CJ., et al. 2006. Plant Physiol. 140: 1222-32. PMID: 16428598
  5. A seizure-induced gain-of-function in BK channels is associated with elevated firing activity in neocortical pyramidal neurons.  |  Shruti, S., et al. 2008. Neurobiol Dis. 30: 323-330. PMID: 18387812
  6. Tricyclic antidepressant amitriptyline alters sarcoplasmic reticulum calcium handling in ventricular myocytes.  |  Zima, AV., et al. 2008. Am J Physiol Heart Circ Physiol. 295: H2008-16. PMID: 18790837
  7. Trifluoperazine: a rynodine receptor agonist.  |  Qin, J., et al. 2009. Pflugers Arch. 458: 643-51. PMID: 19277699
  8. Transglutaminase-mediated intramolecular cross-linking of membrane-bound alpha-synuclein promotes amyloid formation in Lewy bodies.  |  Nemes, Z., et al. 2009. J Biol Chem. 284: 27252-64. PMID: 19651786
  9. Spatial distribution of calcium-gated chloride channels in olfactory cilia.  |  French, DA., et al. 2010. PLoS One. 5: e15676. PMID: 21209888
  10. Calcium modulates force sensing by the von Willebrand factor A2 domain.  |  Jakobi, AJ., et al. 2011. Nat Commun. 2: 385. PMID: 21750539
  11. A method for measuring electrical signals in a primary cilium.  |  Kleene, NK. and Kleene, SJ. 2012. Cilia. 1: 17. PMID: 23308345
  12. The effect of paxilline on early alterations of electrophysiological properties of dentate gyrus granule cells in pilocarpine-treated rats.  |  Mehranfard, N., et al. 2014. Iran J Pharm Res. 13: 125-32. PMID: 24711838
  13. The effect of temperature and ionic strength on the apparent Ca-affinity of EGTA and the analogous Ca-chelators BAPTA and dibromo-BAPTA.  |  Harrison, SM. and Bers, DM. 1987. Biochim Biophys Acta. 925: 133-43. PMID: 3113491
  14. New calcium indicators and buffers with high selectivity against magnesium and protons: design, synthesis, and properties of prototype structures.  |  Tsien, RY. 1980. Biochemistry. 19: 2396-404. PMID: 6770893

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

5,5′-Dibromo-BAPTA, 1 g

sc-273516
1 g
$475.00

5,5′-Dibromo-BAPTA, 5 g

sc-273516A
5 g
$1125.00