Molecular structure of 5,5-Dimethyl-2,4-oxazolidinedione, CAS Number: 695-53-4
5,5-Dimethyl-2,4-oxazolidinedione (CAS 695-53-4)
Alternate Names:
DMO; Dimethadione; NSC 30152
Application:
5,5-Dimethyl-2,4-oxazolidinedione is a reactant used as a cathepsin K inhibitor
CAS Number:
695-53-4
Molecular Weight:
129.11
Molecular Formula:
C5H7NO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
5,5-Dimethyl-2,4-oxazolidinedione is a reactant involved in the synthesis of nickel benzoannulated or naphthoannulated beta-oxatetraazachlorin complex. It can also be used as a cathepsin K inhibitor. While the precise mechanism of action of 5,5-Dimethyl-2,4-oxazolidinedione remains partially understood, it is hypothesized that the compound functions as an inhibitor of voltage-gated sodium channels. These channels play a role in the generation and propagation of electrical signals that regulate the activity of nerve cells.
5,5-Dimethyl-2,4-oxazolidinedione (CAS 695-53-4) References
- Pancreatic excretion of 5, 5-dimethyl-2, 4-oxazolidinedione in normal subjects. | Noda, A., et al. 1975. Am J Dig Dis. 20: 1011-8. PMID: 1199991
- Pancreatic excretion of 5,5-dimethyl-2,4-oxazolidinedione in patients with chronic pancreatitis. | Noda, A., et al. 1975. Am J Dig Dis. 20: 1019-26. PMID: 1199992
- Renal excretion of 5,5-dimethyl-2-4-oxazolidinedione (product of demethylation of trimethadione. | WADDELL, WJ. and BUTLER, TC. 1957. Proc Soc Exp Biol Med. 96: 563-5. PMID: 13505791
- Calculation of intracellular pH from the distribution of 5,5-dimethyl-2,4-oxazolidinedione (DMO); application to skeletal muscle of the dog. | WADDELL, WJ. and BUTLER, TC. 1959. J Clin Invest. 38: 720-9. PMID: 13654506
- The distribution of 5,5-dimethyl-2,4-oxazolidinedione (DMO). II. Studies of the effect of carbonic anhydrase inhibitors and of plasma levels. | CONSTANT, M. 1962. Invest Ophthalmol. 1: 609-17. PMID: 14040462
- The excretion of 5,5-dimethyl-2,4-oxazolidinedione from the canine pancreas and liver. | Noda, A., et al. 1973. Am J Dig Dis. 18: 498-505. PMID: 4705098
- Quantitative gas chromatographic determination of 5,5-dimethyl-2,4-oxazolidinedione. | Marzo, A. and Sardini, D. 1969. J Chromatogr. 44: 611-3. PMID: 5356716
- The movement of 5-5 dimethyl-2,4 oxazolidinedione (DMO) between CSF and plasma. | Kaplan, RJ. and Pollay, M. 1970. Life Sci II. 9: 625-9. PMID: 5478077
- Determination of intramitochondrial pH and intramitochondrial-extramitochondrial pH gradient of isolated heart mitochondria by the use of 5,5-dimethyl-2,4-oxazolidinedione. I. Changes during respiration and adenosine triphosphate-dependent transport of Ca++, Mg++, and Zn++. | Addanki, A., et al. 1968. J Biol Chem. 243: 2337-48. PMID: 5648435
- Distribution of 5,5-dimethyl-2,4-oxazolidinedione (DMO) in intraocular fluids. V. Effect of plasma level, probenecid, and dichlorphenamide on time course. | Constant, MA. 1968. Invest Ophthalmol. 7: 334-46. PMID: 5655878
- Active transport of 5,5-dimethyl-2,4-oxazolidinedione. | Butler, TC. 1966. Science. 151: 1564. PMID: 5930037
- Passive transport of 5,5-dimethyl-2, 4-oxazolidinedione into beef heart mitochondria. | Addanki, S., et al. 1967. Science. 155: 1678-9. PMID: 6020290
- Different mechanisms of action of acetazolamide and parathyroid hormone on proximal tubular absorption of fluid and 5,5-dimethyl-2,4-oxazolidinedione. | Chan, YL. 1980. J Pharmacol Exp Ther. 215: 557-62. PMID: 6255130
- Pancreatolithiasis and pancreatic carcinoma. Evaluation of pancreatic excretion test with 5,5-dimethyl-2,4-oxazolidinedione. | Noda, A., et al. 1977. Arch Intern Med. 137: 754-60. PMID: 869646
Inhibitor of:
cathepsin K.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
5,5-Dimethyl-2,4-oxazolidinedione, 5 g | sc-254861 | 5 g | $120.00 |