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5-(4-Nitrophenyl)-2-furoic acid (CAS 28123-73-1)

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Alternate Names:
5-(4-Nitrophenyl)-2-furancarboxylic acid
CAS Number:
28123-73-1
Molecular Weight:
233.18
Molecular Formula:
C11H7NO5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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5-(4-Nitrophenyl)-2-furoic acid, known as 5-NPFCA, is a remarkably versatile compound with a wide range of applications spanning synthesis, scientific research, and laboratory experiments. Its utility in various scientific research endeavors is noteworthy. It serves as a substrate for studying enzymes like lipases and esterases, facilitating insightful investigations into enzyme kinetics. As a substrate for lipases and esterases, this compound plays a vital role in catalyzing the hydrolysis of the ester bond between the nitrophenyl group and the carboxylic acid group. Consequently, this process leads to the liberation of 4-nitrophenol and furan-2-carboxylic acid, both of which can be further metabolized or employed in other essential reactions. The significance of 5-(4-Nitrophenyl)-2-furoic acid in scientific research cannot be understated, making it an invaluable tool in advancing our understanding of various biochemical processes.


5-(4-Nitrophenyl)-2-furoic acid (CAS 28123-73-1) References

  1. Effect of phosphodiesterase 7 (PDE7) inhibitors in experimental autoimmune encephalomyelitis mice. Discovery of a new chemically diverse family of compounds.  |  Redondo, M., et al. 2012. J Med Chem. 55: 3274-84. PMID: 22385507
  2. Determination of a dantrolene metabolite, 5-(p-nitrophenyl)-2-furoic acid, in plasma and urine by high-performance liquid chromatography.  |  Wuis, EW., et al. 1990. J Chromatogr. 526: 575-80. PMID: 2361999

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

5-(4-Nitrophenyl)-2-furoic acid, 1 g

sc-233182
1 g
$49.00