Date published: 2025-11-15

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5-(2-Aminoethyl)dithio-2-nitrobenzoic Acid (CAS 71899-86-0)

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Application:
5-(2-Aminoethyl)dithio-2-nitrobenzoic Acid is a more base-stable reagent used to quantify thiols
CAS Number:
71899-86-0
Molecular Weight:
274.32
Molecular Formula:
C9H10N2O4S2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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5-(2-Aminoethyl)dithio-2-nitrobenzoic acid (ADTNB) is an organic compound widely utilized in scientific research. Its applications span various fields, including biochemistry, physiology, chemical synthesis, and laboratory experiments. This derivative of dithio-2-nitrobenzoic acid (DTNB) has been extensively studied for its biochemical and physiological effects.In scientific research, 5-(2-Aminoethyl)dithio-2-nitrobenzoic acid serves as useful due to its diverse properties, making it a useful reagent for a wide range of experiments. 5-(2-Aminoethyl)dithio-2-nitrobenzoic acid acts as a potent inhibitor of thiol-dependent enzymes like thioredoxin reductase and glutathione reductase. Moreover, it hinders the formation of disulfide bonds, which play a role in the proper functioning of proteins.


5-(2-Aminoethyl)dithio-2-nitrobenzoic Acid (CAS 71899-86-0) References

  1. 2,4-Dinitrobenzenesulfonyl fluoresceins as fluorescent alternatives to Ellman's reagent in thiol-quantification enzyme assays.  |  Maeda, H., et al. 2005. Angew Chem Int Ed Engl. 44: 2922-5. PMID: 15818626
  2. Detection of Thiol Functionality and Disulfide Bond Formation by Polyoxometalate.  |  Konno, H., et al. 2020. ACS Comb Sci. 22: 745-749. PMID: 33030888
  3. Coenzyme Q10 protected against arsenite and enhanced the capacity of 2,3-dimercaptosuccinic acid to ameliorate arsenite-induced toxicity in mice.  |  Mwaeni, VK., et al. 2021. BMC Pharmacol Toxicol. 22: 19. PMID: 33827703
  4. Synthesis and membrane interactions of spin-label bifunctional reagents.  |  Gaffney, BJ., et al. 1983. Biochemistry. 22: 881-92. PMID: 6301528
  5. Reactions of spin-label cross-linking reagents with red blood cell proteins.  |  Willingham, GL. and Gaffney, BJ. 1983. Biochemistry. 22: 892-8. PMID: 6301529

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

5-(2-Aminoethyl)dithio-2-nitrobenzoic Acid, 10 mg

sc-214299
10 mg
$260.00