Date published: 2025-10-21

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(4R)-4-(2-Hydroxyethyl)-2,2-dimethyl-1,3-dioxolane (CAS 70005-89-9)

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CAS Number:
70005-89-9
Molecular Weight:
146.18
Molecular Formula:
C7H14O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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The organic compound, (4R)-4-(2-Hydroxyethyl)-2,2-dimethyl-1,3-dioxolane, referred to as HDMD, falls within the dioxolane category. Serving as a initial substance, it contributes to the creation of diverse agrochemicals, and compounds. (4R)-4-(2-Hydroxyethyl)-2,2-dimethyl-1,3-dioxolane functions as a versatile reagent, finding utility across numerous scientific research applications.(4R)-4-(2-Hydroxyethyl)-2,2-dimethyl-1,3-dioxolane finds extensive use in various scientific research domains. It participates in the synthesis of agrochemicals, and polymer materials. Additionally, it plays a role in generating peptides, proteins, and organometallic compounds. This compound has also contributed to the formation of assorted heterocyclic compounds like imidazoles and thiazoles. The operational mechanism of (4R)-4-(2-Hydroxyethyl)-2,2-dimethyl-1,3-dioxolane centers around its capacity to generate a nucleophilic bromonium ion. This ion is subsequently attacked by DMSO, leading to the desired product′s formation. Reactions usually conclude within 1-2 hours, transpiring at temperatures ranging between 80-90° C.


(4R)-4-(2-Hydroxyethyl)-2,2-dimethyl-1,3-dioxolane (CAS 70005-89-9) References

  1. The first total synthesis of cytopiloyne, an anti-diabetic, polyacetylenic glucoside.  |  Kumar, CR., et al. 2011. Chemistry. 17: 8696-703. PMID: 21681841
  2. Total synthesis of the lipid mediator PD1n-3 DPA: configurational assignments and anti-inflammatory and pro-resolving actions.  |  Aursnes, M., et al. 2014. J Nat Prod. 77: 910-6. PMID: 24576195

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

(4R)-4-(2-Hydroxyethyl)-2,2-dimethyl-1,3-dioxolane, 5 g

sc-254755
5 g
$265.00