Date published: 2026-6-4

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4′-Nitrobenzo-15-crown-5 (CAS 60835-69-0)

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CAS Number:
60835-69-0
Molecular Weight:
313.30
Molecular Formula:
C14H19NO7
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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4-Nitrobenzo-15-crown-5 (4-NB-15-5) is an intriguing organic compound that falls within the family of crown ethers. This cyclic ether is composed of 15 atoms and stands out with a distinctive nitro group located at the 4 position of its aromatic ring. Due to its remarkable properties, extensive research has been conducted on 4′-Nitrobenzo-15-crown-5, leading to its widespread use across various scientific domains, including organic synthesis, biochemistry, and materials science. In scientific research, 4-Nitrobenzo-15-crown-5 has proven to be highly versatile. Its applications include serving as a complexing agent for transition metals, acting as a ligand for metal ions, and participating in the study of self-assembly of metal-organic frameworks. Additionally, it has been recognized as an inhibitor of enzymes and a receptor for both anions and cations. The mechanism behind the action of 4-Nitrobenzo-15-crown-5 is closely tied to its ability to form complexes with metal ions. The presence of its nitro group enables the formation of strong bonds with metal ions, which accounts for its exceptional complexing ability. Moreover, its role as a ligand for metal ions explains the inhibitory effects it exerts on enzymes.


4′-Nitrobenzo-15-crown-5 (CAS 60835-69-0) References

  1. Photometric reagents for alkali metal ions, based on crown-ether complex formation--III. 4'-picrylaminobenzo-15-crown-5 derivatives.  |  Nakamura, H., et al. 1979. Talanta. 26: 921-7. PMID: 18962544
  2. Codeposition Modification of Cation Exchange Membranes with Dopamine and Crown Ether To Achieve High K+ Electrodialysis Selectivity.  |  Yang, S., et al. 2019. ACS Appl Mater Interfaces. 11: 17730-17741. PMID: 31013045
  3. Study on improvement of chiral separation of capillary electrophoresis based on cyclodextrin by deep eutectic solvents.  |  Deng, S., et al. 2020. Talanta. 220: 121419. PMID: 32928430
  4. An ion-selective crown ether covalently grafted onto chemically exfoliated MoS2 as a biological fluid sensor.  |  Stergiou, A., et al. 2021. Nanoscale. 13: 8948-8957. PMID: 33960349
  5. All-Solid-State Potentiometric Platforms Modified with a Multi-Walled Carbon Nanotubes for Fluoxetine Determination.  |  Abd-Rabboh, HSM., et al. 2022. Membranes (Basel). 12: PMID: 35629772
  6. Non-Enzymatic Phenylboronic Acid-Based Optode Membrane for Glucose Monitoring in Serums of Diabetic Patients and in the Culture Medium of Human Embryos.  |  Taha, MM., et al. 2022. Sensors (Basel). 22: PMID: 36236234
  7. Potentiometric digoxin antibody measurements with antigen-ionophore based membrane electrodes.  |  Keating, MY. and Rechnitz, GA. 1984. Anal Chem. 56: 801-6. PMID: 6721153

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4′-Nitrobenzo-15-crown-5, 1 g

sc-233125
1 g
$163.00