Date published: 2026-4-25

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4′-Hydroxyflavanone (CAS 6515-37-3)

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CAS Number:
6515-37-3
Molecular Weight:
240.25
Molecular Formula:
C15H12O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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4′-Hydroxyflavanone is a flavanone compound and can be found in various fruits, such as citrus fruits like grapefruit and oranges. Inhibits lipid synthesis by inhibiting the enzymes 4-hydroxylase and acetyl-CoA carboxylase, which play a role in fatty acid and acetate synthesis. Used as a natural antioxidant in food and drink industries. Used as a reference standard in HPLC and MS analyses of flavonoids.


4′-Hydroxyflavanone (CAS 6515-37-3) References

  1. Regiospecificity of human UDP-glucuronosyltransferase isoforms in chalcone and flavanone glucuronidation determined by metal complexation and tandem mass spectrometry.  |  Niemeyer, ED. and Brodbelt, JS. 2013. J Nat Prod. 76: 1121-32. PMID: 23713759
  2. [Study on Fluorescence Properties of Flavanone and Its Hydroxyl Derivatives].  |  Li, WH., et al. 2016. Guang Pu Xue Yu Guang Pu Fen Xi. 36: 1007-12. PMID: 30048098
  3. Local Phenomena Shape Backyard Soil Metabolite Composition.  |  Nguyen, TD., et al. 2020. Metabolites. 10: PMID: 32121389
  4. Expression and functional analysis of the nobiletin biosynthesis-related gene CitOMT in citrus fruit.  |  Seoka, M., et al. 2020. Sci Rep. 10: 15288. PMID: 32943728
  5. Naturally Occurring Flavonoids and Isoflavonoids and Their Microbial Transformation: A Review.  |  Wang, JF., et al. 2020. Molecules. 25: PMID: 33153224
  6. Potential Benefits of Flavonoids on the Progression of Atherosclerosis by Their Effect on Vascular Smooth Muscle Excitability.  |  Grijalva-Guiza, RE., et al. 2021. Molecules. 26: PMID: 34200914
  7. Effects of naringenin supplementation in overweight/obese patients with non-alcoholic fatty liver disease: study protocol for a randomized double-blind clinical trial.  |  Naeini, F., et al. 2021. Trials. 22: 801. PMID: 34774104
  8. The Hidden One: What We Know About Bitter Taste Receptor 39.  |  Jalševac, F., et al. 2022. Front Endocrinol (Lausanne). 13: 854718. PMID: 35345470
  9. Preparation of a novel bridged bis(β-cyclodextrin) chiral stationary phase by thiol-ene click chemistry for enhanced enantioseparation in HPLC.  |  Zhang, N., et al. 2021. RSC Adv. 11: 35754-35764. PMID: 35492805
  10. Novel O-Methylglucoside Derivatives of Flavanone in Interaction with Model Membrane and Transferrin.  |  Cyboran-Mikołajczyk, S., et al. 2022. Membranes (Basel). 12: PMID: 36295737
  11. Porous Organic Cage-Embedded C10-Modified Silica as HPLC Stationary Phase and Its Multiple Separation Functions.  |  Wang, L., et al. 2022. Molecules. 27: PMID: 36558026
  12. The phytochemicals and health benefits of Cyclocarya paliurus (Batalin) Iljinskaja.  |  Shen, Y., et al. 2023. Front Nutr. 10: 1158158. PMID: 37090775
  13. Molecular characterization of a flavanone 3-hydroxylase gene from citrus fruit reveals its crucial roles in anthocyanin accumulation.  |  Ma, G., et al. 2023. BMC Plant Biol. 23: 233. PMID: 37131162

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4′-Hydroxyflavanone, 1 g

sc-233119
1 g
$231.00