4′-Hydroxy Diclofenac (CAS 64118-84-9)
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4′-Hydroxy Diclofenac is a major metabolite of diclofenac, emerging through the metabolic pathways involving cytochrome P450 enzymes, particularly CYP2C9. This compound plays a role in the research landscape, particularly in the study of drug metabolism and the elucidation of mechanisms related to the biotransformation of pharmaceutical compounds. Its formation is indicative of the phase I metabolic processes that xenobiotics undergo, highlighting the significance of oxidative reactions in altering the molecular structure and properties of substances to enhance their excretion. In research applications, 4′-Hydroxy Diclofenac serves as a model compound to investigate the kinetics of metabolic reactions, the impact of genetic polymorphisms on drug metabolism, and the potential for drug-drug interactions mediated by the cytochrome P450 system. This metabolite′s presence and concentration in various models can provide insight into the efficiency of drug metabolism and the potential for accumulation of parent compounds or their metabolites.
4′-Hydroxy Diclofenac (CAS 64118-84-9) References
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
4′-Hydroxy Diclofenac, 1 mg | sc-202423 | 1 mg | $173.00 | |||
4′-Hydroxy Diclofenac, 5 mg | sc-202423A | 5 mg | $624.00 |