Date published: 2026-5-25

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4′-Dimethylaminoacetophenone (CAS 2124-31-4)

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Alternate Names:
1-(4-(Dimethylamino)phenyl)ethanone
CAS Number:
2124-31-4
Molecular Weight:
163.2
Molecular Formula:
C10H13NO
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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4′-Dimethylaminoacetophenone, known as 4-DMA, is an organic compound categorized as a phenylketone. It finds extensive applications in the synthesis of agrochemicals and various organic compounds due to its versatile nature as an aromatic amine. This compound serves as a building block in the creation of numerous essential compounds. Numerous studies have delved into the potential uses of 4′-Dimethylaminoacetophenone in organic synthesis, specifically in the development of agrochemicals and other organic compounds. While the exact mechanism of action of 4′-Dimethylaminoacetophenone remains not entirely understood, it is believed to act as a catalyst during the synthesis of diverse organic compounds. Its role is thought to facilitate reactions involving a nucleophile and an aldehyde or ketone, resulting in the desired product formation. Moreover, the compound is believed to function as a reducing agent, effectively lowering the energy requirements for completing these reactions.


4′-Dimethylaminoacetophenone (CAS 2124-31-4) References

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  5. A long lasting sunscreen controversy of 4-aminobenzoic acid and 4-dimethylaminobenzaldehyde derivatives resolved by ultrafast spectroscopy combined with density functional theoretical study.  |  Chan, CT., et al. 2020. Phys Chem Chem Phys. 22: 8006-8020. PMID: 32239002
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  7. The role of the angle of pretwist of some molecules forming twisted intramolecular charge transfer (TICT) states in polymer matrices  |  Khader A. Al-Hassan 1, Tohru Azumi, Wolfgang Rettig. 1993. Chemical Physics Letters. 206: 25-29.
  8. Intramolecular sensitisation of lanthanide(III) luminescence by acetophenone-containing ligands: the critical effect of para-substituents and solvent  |  Andrew Beeby *, Lisa M. Bushby, Davide Maffeo and J. A. Gareth Williams *. 2002. J. Chem. Soc., Dalton Trans. 48-54.
  9. The cavity size effect on the fluorescence properties of 4′-dimethylaminoacetophenone complexed with cyclodextrins  |  Y. Matsushita a, T. Suzuki b, T. Ichimura b, T. Hikida c. 2003. Chemical Physics. 286: 399-407.
  10. Reductants for polyperoxides to accelerate degradation at elevated temperatures  |  Eriko Sato a, Michihiro Yuri a, Akikazu Matsumoto b, Hideo Horibe a. 2019. Polymer Degradation and Stability. 162: 47-54.
  11. Photochemistry of 5-Hydroxy-4'-Dimethylaminoflavylium in the presence of SDS micelles. The role of metastable states of flavylium cation-quinoidal base and trans-chalcones  |  Paula Araújo a, Johan Mendoza b, Fernando Pina b, Ana Rita Pereira a, Iva Fernandes a, Victor de Freitas a, Joana Oliveira a. 2020. Journal of Photochemistry and Photobiology A: Chemistry. 402.
  12. Synthesis, structural characterization and chromatic features of new 2-phenyl-1-benzopyrylium and 2-phenyl-styryl-1-benzopyrylium amino-based blue dyes  |  Paula Araújo, Ana Rita Pereira, Victor de Freitas, Nuno Mateus, Iva Fernandes, Joana Oliveira. 2021. Tetrahedron Letters. 85.
  13. Two novel mono-hydroxyl pyranoanthocyanidins bearing dimethylamino substituent(s) for dye-sensitized solar cell  |  Xiaolong Shi a b, Yuanzuo Li c, Lihai Wang a. 2022. Journal of Molecular Structure. 1252.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4′-Dimethylaminoacetophenone, 5 g

sc-323303
5 g
$32.00

4′-Dimethylaminoacetophenone, 25 g

sc-323303A
25 g
$103.00