Date published: 2025-9-17

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4F 4PP oxalate (CAS 144734-36-1)

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Alternate Names:
4-(4-Fluorobenzoyl)-1-(4-phenylbutyl)piperidine oxalate
Application:
4F 4PP oxalate is a selective SR-2A antagonist
CAS Number:
144734-36-1
Molecular Weight:
429.49
Molecular Formula:
C22H26FNO•C2H2O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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4F 4PP oxalate is used in research to investigate its interaction with various biological targets, often focusing on the nervous system due to its structural features that resemble those of biologically active compounds. Its role in binding studies helps in elucidating the affinity and selectivity towards specific receptors or enzymes, which is for understanding signaling pathways. Research on this compound contributes to the field of chemical biology by providing insights into the modulation of physiological processes. Additionally, its oxalate salt form is of interest due to its potential influence on the compound′s solubility and stability, which are important parameters in experimental design and the development of assay systems.


4F 4PP oxalate (CAS 144734-36-1) References

  1. 5-Hydroxytryptamine2B receptors stimulate Ca2+ increases in cultured astrocytes from three different brain regions.  |  Sandén, N., et al. 2000. Neurochem Int. 36: 427-34. PMID: 10733010
  2. A population of glomerular glutamatergic neurons controls sensory information transfer in the mouse olfactory bulb.  |  Tatti, R., et al. 2014. Nat Commun. 5: 3791. PMID: 24804702
  3. Estrogen receptor β deficiency impairs BDNF-5-HT2A signaling in the hippocampus of female brain: A possible mechanism for menopausal depression.  |  Chhibber, A., et al. 2017. Psychoneuroendocrinology. 82: 107-116. PMID: 28544903
  4. Fenfluramine diminishes NMDA receptor-mediated seizures via its mixed activity at serotonin 5HT2A and type 1 sigma receptors.  |  Rodríguez-Muñoz, M., et al. 2018. Oncotarget. 9: 23373-23389. PMID: 29805740
  5. 5-HT2A Receptor-Induced Morphological Reorganization of PKCγ-Expressing Interneurons Gates Inflammatory Mechanical Allodynia in Rat.  |  Alba-Delgado, C., et al. 2018. J Neurosci. 38: 10489-10504. PMID: 30355630
  6. Stimulation of 5-HT2A receptors on astrocytes in primary culture opens voltage-independent Ca2+ channels.  |  Hagberg, GB., et al. 1998. Neurochem Int. 32: 153-62. PMID: 9542727

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4F 4PP oxalate, 10 mg

sc-203782
10 mg
$224.00

4F 4PP oxalate, 50 mg

sc-203782A
50 mg
$930.00