Molecular structure of 4-(Trifluoromethyl)phenol, CAS Number: 402-45-9
4-(Trifluoromethyl)phenol (CAS 402-45-9)
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Alternate Names:
α,α,α-Trifluoro-p-cresol
Application:
4-(Trifluoromethyl)phenol is a synthesis reagent used for diaryl ether
CAS Number:
402-45-9
Molecular Weight:
162.11
Molecular Formula:
C7H5F3O
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
4-(Trifluoromethyl)phenol functions as a building block in organic synthesis. It is known for its ability to participate in various chemical reactions, including nucleophilic aromatic substitution, electrophilic aromatic substitution, and transition metal-catalyzed cross-coupling reactions. 4-(Trifluoromethyl)Phenol′s mechanism of action involves its reactivity with other organic molecules, leading to the formation of new carbon-carbon or carbon-heteroatom bonds. In experimental applications, 4-(Trifluoromethyl)phenol is utilized for the synthesis of agrochemicals and materials with specific properties. Its molecular structure allows it to serve as a versatile intermediate in the preparation of complex organic compounds.
4-(Trifluoromethyl)phenol (CAS 402-45-9) References
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- A fine-tuned molybdenum hexacarbonyl/phenol initiator for alkyne metathesis. | Sashuk, V., et al. 2004. J Org Chem. 69: 7748-51. PMID: 15498008
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- Regio- and stereospecific formation of protected allylic alcohols via zirconium-mediated S(N)2' substitution of allylic chlorides. | Fox, RJ., et al. 2007. J Am Chem Soc. 129: 14144-5. PMID: 17973391
- Mechanistic studies in biodegradation of the new synthesized fluorosurfactant 9-[4-(trifluoromethyl)phenoxy]nonane-1-sulfonate. | Peschka, M., et al. 2008. J Chromatogr A. 1187: 79-86. PMID: 18295223
- Influence of photolabile pharmaceuticals on the photodegradation and toxicity of fluoxetine and fluvoxamine. | Wawryniuk, M., et al. 2018. Environ Sci Pollut Res Int. 25: 6890-6898. PMID: 29270897
- Analytical and ecotoxicological studies on degradation of fluoxetine and fluvoxamine by potassium ferrate. | Drzewicz, P., et al. 2019. Environ Technol. 40: 3265-3275. PMID: 29756529
- Photogeneration of Quinone Methides as Latent Electrophiles for Lysine Targeting. | Pérez-Ruiz, R., et al. 2018. J Org Chem. 83: 13019-13029. PMID: 30274513
- Bacterial degradation of the anti-depressant drug fluoxetine produces trifluoroacetic acid and fluoride ion. | Khan, MF. and Murphy, CD. 2021. Appl Microbiol Biotechnol. 105: 9359-9369. PMID: 34755212
- Clinical management, antiviral drugs and immunotherapeutics for treating monkeypox. An update on current knowledge and futuristic prospects. | Chakraborty, S., et al. 2022. Int J Surg. 105: 106847. PMID: 35995352
- 1H and 19F-nmr spectroscopic studies on the metabolism and urinary excretion of mono- and disubstituted phenols in the rat. | Bollard, ME., et al. 1996. Xenobiotica. 26: 255-73. PMID: 8730918
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
4-(Trifluoromethyl)phenol, 1 g | sc-254583 | 1 g | $26.00 | |||
4-(Trifluoromethyl)phenol, 5 g | sc-254583A | 5 g | $83.00 |