Molecular structure of 4-(Trifluoromethyl)-L-phenylglycine, CAS Number: 144789-75-3
4-(Trifluoromethyl)-L-phenylglycine (CAS 144789-75-3)
Alternate Names:
(S)-2-Amino-2-[4-(trifluoromethyl)phenyl]acetic acid
CAS Number:
144789-75-3
Molecular Weight:
219.16
Molecular Formula:
C9H8F3NO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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4-(Trifluoromethyl)-L-phenylglycine, known as TFMPH, is an amino acid derivative that has found widespread use in various scientific research endeavors. Serving as an analog to phenylalanine, a naturally occurring amino acid, 4-(Trifluoromethyl)-L-phenylglycine enables the investigation of the biochemical and physiological effects associated with its parent compound. In scientific research applications, 4-(Trifluoromethyl)-L-phenylglycine has been employed to explore the modulation of enzymes, receptors, and transporters, as well as to delve into gene expression regulation and signal transduction pathways.
4-(Trifluoromethyl)-L-phenylglycine (CAS 144789-75-3) References
- In silico re-engineering of a neurotransmitter to activate KCNQ potassium channels in an isoform-specific manner. | Manville, RW. and Abbott, GW. 2019. Commun Biol. 2: 401. PMID: 31701029
- Isoform-Selective KCNA1 Potassium Channel Openers Built from Glycine. | Manville, RW. and Abbott, GW. 2020. J Pharmacol Exp Ther. 373: 391-401. PMID: 32217768
- Severe deficiency of the voltage-gated sodium channel NaV1.2 elevates neuronal excitability in adult mice. | Zhang, J., et al. 2021. Cell Rep. 36: 109495. PMID: 34348148
- Hyperexcitability in adult mice with severe deficiency in NaV1.2 channels. | Nadella, N., et al. 2022. Int J Physiol Pathophysiol Pharmacol. 14: 55-59. PMID: 35310859
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| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
4-(Trifluoromethyl)-L-phenylglycine, 1 g | sc-226439 | 1 g | $142.00 |