Molecular structure of 4-Thiouridine-5′-O-(β,γ-difluoromethylene)triphosphate tetrasodium salt, CAS Number: 1657025-60-9
4-Thiouridine-5′-O-(β,γ-difluoromethylene)triphosphate tetrasodium salt (CAS 1657025-60-9)
Alternate Names:
PSB 1114
Application:
4-Thiouridine-5′-O-(β,γ-difluoromethylene)triphosphate tetrasodium salt is a selective and potent P2Y2 agonist
CAS Number:
1657025-60-9
Molecular Weight:
622.14
Molecular Formula:
C10H11F2N2Na4O13P3S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
4-Thiouridine-5′-O-(β,γ-difluoromethylene)triphosphate tetrasodium salt is a selective and potent P2Y2 agonist.
4-Thiouridine-5′-O-(β,γ-difluoromethylene)triphosphate tetrasodium salt (CAS 1657025-60-9) References
- Pharmacology and structure of P2Y receptors. | von Kügelgen, I. and Hoffmann, K. 2016. Neuropharmacology. 104: 50-61. PMID: 26519900
- Tools and drugs for uracil nucleotide-activated P2Y receptors. | Rafehi, M. and Müller, CE. 2018. Pharmacol Ther. 190: 24-80. PMID: 29660366
- Molecular pharmacology of P2Y receptor subtypes. | von Kügelgen, I. 2021. Biochem Pharmacol. 187: 114361. PMID: 33309519
- Nucleic acid ligands act as a PAM and agonist depending on the intrinsic ligand binding state of P2RY2. | Takahashi, M., et al. 2021. Proc Natl Acad Sci U S A. 118: PMID: 33911033
- P2Y2 promotes fibroblasts activation and skeletal muscle fibrosis through AKT, ERK, and PKC. | Chen, M., et al. 2021. BMC Musculoskelet Disord. 22: 680. PMID: 34380439
- Therapeutic potential for P2Y2 receptor antagonism. | Jasmer, KJ., et al. 2022. Purinergic Signal.. PMID: 36219327
Activator of:
P2Y2.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
4-Thiouridine-5′-O-(β,γ-difluoromethylene)triphosphate tetrasodium salt, 1 mg | sc-362785 | 1 mg | $2600.00 |