Date published: 2026-5-4

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4-tert-Octylphenol Diethoxylate (CAS 2315-61-9)

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Alternate Names:
OP2EO; 2-{2-[4-(1,1,3,3-Tetramethylbutyl)phenoxy]ethoxy}ethanol
Application:
4-tert-Octylphenol Diethoxylate is a common environmental pollutant showing weak estrogenic effects
CAS Number:
2315-61-9
Molecular Weight:
294.43
Molecular Formula:
C18H30O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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4-tert-Octylphenol Diethoxylate is a common environmental pollutant showing weak estrogenic effects. It may act to cause harm to the male reproductive system of vertebrates. In scientific research, it is mainly used as a solvent, an extractant, a stabilizer, a non-ionic surfactant, and as a reagent in organic synthesis. It has been utilized in a variety of studies on the effects of compounds on cell viability, cell proliferation, and other cellular processes.


4-tert-Octylphenol Diethoxylate (CAS 2315-61-9) References

  1. Inhibition of rat hepatic cytochrome P450 activities by biodegradation products of 4-tert-octylphenol ethoxylate.  |  Hanioka, N., et al. 1999. Xenobiotica. 29: 873-83. PMID: 10548448
  2. The occurrence of xenoestrogens in the Elbe river and the North Sea.  |  Heemken, OP., et al. 2001. Chemosphere. 45: 245-59. PMID: 11592413
  3. Isolation and identification of Sphingomonas sp. that yields tert-octylphenol monoethoxylate under aerobic conditions.  |  Nishio, E., et al. 2005. Biosci Biotechnol Biochem. 69: 1226-31. PMID: 16041123
  4. Reproductive responses of male fathead minnows exposed to wastewater treatment plant effluent, effluent treated with XAD8 resin, and an environmentally relevant mixture of alkylphenol compounds.  |  Barber, LB., et al. 2007. Aquat Toxicol. 82: 36-46. PMID: 17331597
  5. Reproductive disruption in fish downstream from an estrogenic wastewater effluent.  |  Vajda, AM., et al. 2008. Environ Sci Technol. 42: 3407-14. PMID: 18522126
  6. 4-tert-Octylphenol stimulates the expression of cathepsins in human breast cancer cells and xenografted breast tumors of a mouse model via an estrogen receptor-mediated signaling pathway.  |  Lee, HR. and Choi, KC. 2013. Toxicology. 304: 13-20. PMID: 23219593
  7. Liquid chromatographic-tandem mass spectrometric method for the simultaneous determination of alkylphenols polyethoxylates, alkylphenoxy carboxylates and alkylphenols in wastewater and surface-water.  |  Ciofi, L., et al. 2014. J Chromatogr A. 1362: 75-88. PMID: 25171944
  8. Fully automated on-line solid phase extraction coupled to liquid chromatography-tandem mass spectrometry for the simultaneous analysis of alkylphenol polyethoxylates and their carboxylic and phenolic metabolites in wastewater samples.  |  Ciofi, L., et al. 2016. Anal Bioanal Chem. 408: 3331-47. PMID: 26897380
  9. Organic contaminants in Great Lakes tributaries: Prevalence and potential aquatic toxicity.  |  Baldwin, AK., et al. 2016. Sci Total Environ. 554-555: 42-52. PMID: 26950618
  10. Consumer Product Chemicals in Indoor Dust: A Quantitative Meta-analysis of U.S. Studies.  |  Mitro, SD., et al. 2016. Environ Sci Technol. 50: 10661-10672. PMID: 27623734
  11. Prioritization of Contaminants of Emerging Concern in Wastewater Treatment Plant Discharges Using Chemical:Gene Interactions in Caged Fish.  |  Perkins, EJ., et al. 2017. Environ Sci Technol. 51: 8701-8712. PMID: 28651047
  12. Pharmaceuticals, hormones, pesticides, and other bioactive contaminants in water, sediment, and tissue from Rocky Mountain National Park, 2012-2013.  |  Battaglin, WA., et al. 2018. Sci Total Environ. 643: 651-673. PMID: 29957431
  13. Current contamination status of traditional and emerging persistent toxic substances in the sediments of Ulsan Bay, South Korea.  |  An, Y., et al. 2020. Mar Pollut Bull. 160: 111560. PMID: 32841802
  14. Identification of core micropollutants of Ergene River and their categorization based on spatiotemporal distribution.  |  Emadian, SM., et al. 2021. Sci Total Environ. 758: 143656. PMID: 33261876
  15. [Usefulness of estriol for the treatment of bone loss in postmenopausal women].  |  Nozaki, M., et al. 1996. Nihon Sanka Fujinka Gakkai Zasshi. 48: 83-8. PMID: 8718542

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4-tert-Octylphenol Diethoxylate, 10 mg

sc-210156
10 mg
$343.00