Date published: 2026-1-20

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4-tert-Butyl-2,6-dimethylaniline (CAS 42014-60-8)

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CAS Number:
42014-60-8
Molecular Weight:
177.29
Molecular Formula:
C12H19N
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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4-tert-Butyl-2,6-dimethylaniline is a compound that functions as a reagent in organic synthesis. It acts as a nucleophilic catalyst, participating in various reactions such as Friedel-Crafts acylation and alkylation. The compound′s mechanism of action involves its ability to donate electrons and form covalent bonds with other molecules, facilitating the formation of new carbon-carbon and carbon-heteroatom bonds. This allows for the synthesis of complex organic molecules with high selectivity and efficiency. 4-tert-Butyl-2,6-dimethylaniline can act as a ligand in transition metal-catalyzed reactions, enhancing the reactivity and selectivity of the catalytic process. Its molecular structure and electronic properties make it a versatile functioning for the construction of diverse chemical structures, making it a asset in the development of new materials and compounds.


4-tert-Butyl-2,6-dimethylaniline (CAS 42014-60-8) References

  1. Crystal structure of 2,3-bis-[(4-tert-butyl-2,6-di-methyl-phen-yl)imino]-butane.  |  Zhao, SL., et al. 2015. Acta Crystallogr E Crystallogr Commun. 71: o258. PMID: 26029444
  2. Isocyanides as Influenza A Virus Subtype H5N1 Wild-Type M2 Channel Inhibitors.  |  Wu, S., et al. 2015. ChemMedChem. 10: 1837-45. PMID: 26506405
  3. Formal group insertion into aryl C‒N bonds through an aromaticity destruction-reconstruction process.  |  Han, D., et al. 2018. Nat Commun. 9: 3423. PMID: 30143605

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4-tert-Butyl-2,6-dimethylaniline, 100 mg

sc-262163
100 mg
$52.00

4-tert-Butyl-2,6-dimethylaniline, 1 g

sc-262163A
1 g
$176.00