Date published: 2026-5-3

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4-Sulfocalix[4]arene (CAS 112269-92-8)

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Alternate Names:
Tetrahydroxycalix[4]arenetetrasulfonic Acid; Tetrasulfo(tetrahydroxy)calix[4]arene
CAS Number:
112269-92-8
Molecular Weight:
744.74
Molecular Formula:
C28H24O16S4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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4-Sulfocalix[4]arene is a macrocyclic compound that belongs to the family of calixarenes, which are cyclic oligomers derived from phenols. 4-Sulfocalix[4]arene is characterized by its unique structure, which consists of four sulfonate groups attached to a calix[4]arene framework. The presence of these sulfonate groups imparts water solubility to the molecule, making it suitable for various biochemical applications. 4-Sulfocalix[4]arene has been studied for its ability to encapsulate guest molecules within its cavity, making it a promising candidate for the development of host-guest systems. Its water solubility and structural flexibility make it for the design of supramolecular assemblies and biomimetic systems. In biochemistry, 4-Sulfocalix[4]arene is of interest due to its potential to interact with biomolecules and its role in the development of novel materials for biological applications.


4-Sulfocalix[4]arene (CAS 112269-92-8) References

  1. Green synthesis and characterization of novel gold nanocomposites for electrochemical sensing applications.  |  Tanwar, S., et al. 2013. Talanta. 117: 352-8. PMID: 24209352
  2. Self-assemblies based on the 'outer-surface interactions' of cucurbit[n]urils: new opportunities for supramolecular architectures and materials.  |  Ni, XL., et al. 2014. Acc Chem Res. 47: 1386-95. PMID: 24673124
  3. Lateral assembly of oxidized graphene flakes into large-scale transparent conductive thin films with a three-dimensional surfactant 4-sulfocalix[4]arene.  |  Sundramoorthy, AK., et al. 2015. Sci Rep. 5: 10716. PMID: 26040436
  4. Investigation of the host-guest complexation between 4-sulfocalix[4]arene and nedaplatin for potential use in drug delivery.  |  Fahmy, SA., et al. 2018. Spectrochim Acta A Mol Biomol Spectrosc. 193: 528-536. PMID: 29306207
  5. Enantioselective recognition of chiral acids by supramolecular interactions with chiral AIEgens.  |  Xiang, S., et al. 2021. Chem Commun (Camb). 57: 13321-13324. PMID: 34814159
  6. Supramolecular Polymer Network Membranes with Molecular-Sieving Nanocavities for Efficient Pre-Combustion CO2 Capture.  |  Wu, J. and Chung, TS. 2022. Small Methods. 6: e2101288. PMID: 35041282

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4-Sulfocalix[4]arene, 250 mg

sc-290491B
250 mg
$123.00

4-Sulfocalix[4]arene, 1 g

sc-290491
1 g
$196.00

4-Sulfocalix[4]arene, 5 g

sc-290491A
5 g
$958.00