Date published: 2026-4-28

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4-Quinolinecarboxylic acid (CAS 486-74-8)

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CAS Number:
486-74-8
Molecular Weight:
173.17
Molecular Formula:
C10H7NO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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4-Quinolinecarboxylic acid is a heterocyclic organic compound present in diverse plants, fungi, and bacteria. As an intermediate in compound synthesis, it has garnered attention for applications in in vitro experiments. Researchers have utilized 4-Quinolinecarboxylic acid to explore the impact of gene expression on cell viability and to elucidate the mechanism of action of specific drugs.


4-Quinolinecarboxylic acid (CAS 486-74-8) References

  1. Identification of selective and potent inhibitors of fibroblast activation protein and prolyl oligopeptidase.  |  Poplawski, SE., et al. 2013. J Med Chem. 56: 3467-77. PMID: 23594271
  2. The 3,7-diazabicyclo[3.3.1]nonane scaffold for subtype selective nicotinic acetylcholine receptor (nAChR) ligands. Part 1: the influence of different hydrogen bond acceptor systems on alkyl and (hetero)aryl substituents.  |  Eibl, C., et al. 2013. Bioorg Med Chem. 21: 7283-308. PMID: 24156938
  3. Metabolome-wide association study of phenylalanine in plasma of common marmosets.  |  Go, YM., et al. 2015. Amino Acids. 47: 589-601. PMID: 25526869
  4. Evaluation of the serum metabolome of patients with alkaptonuria before and after two years of treatment with nitisinone using LC-QTOF-MS.  |  Davison, AS., et al. 2019. JIMD Rep. 48: 67-74. PMID: 31392115
  5. Alkaloid Enantiomers from the Roots of Isatis indigotica.  |  Zhang, D., et al. 2019. Molecules. 24: PMID: 31470525
  6. Metabolomic analysis of primary human skeletal muscle cells during myogenic progression.  |  Kumar, A., et al. 2020. Sci Rep. 10: 11824. PMID: 32678274
  7. Metabolomics profiles of premenopausal women are different based on O-desmethylangolensin metabotype.  |  Frankenfeld, CL., et al. 2022. Br J Nutr. 128: 1490-1498. PMID: 34763731
  8. Exploring the formation mechanism of off-flavor of irradiated yak meat based on metabolomics.  |  Wang, Q., et al. 2022. Food Chem X. 16: 100494. PMID: 36519093
  9. Design and Synthesis of Conformationally Flexible Scaffold as Bitopic Ligands for Potent D3-Selective Antagonists.  |  Kim, HY., et al. 2022. Int J Mol Sci. 24: PMID: 36613875
  10. Activity of a novel 4-quinolinecarboxylic acid, NSC 368390 [6-fluoro-2-(2'-fluoro-1,1'-biphenyl-4-yl)-3-methyl-4-quinolinecarb oxylic acid sodium salt], against experimental tumors.  |  Dexter, DL., et al. 1985. Cancer Res. 45: 5563-8. PMID: 4053030

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4-Quinolinecarboxylic acid, 1 g

sc-238953
1 g
$75.00