4-Piperazinobenzonitrile (CAS 68104-63-2)
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4-Piperazinobenzonitrile is a chemical used primarily as an intermediate in the synthesis of more complex organic molecules. It offers versatility in chemical research due to the presence of both a piperazine ring and a benzonitrile group, which can undergo various chemical reactions to yield a wide range of products. This compound is often employed in the creation of small molecule libraries that are used in high-throughput screening for compound activity. In the field of organic chemistry, researchers utilize 4-piperazinobenzonitrile′s reactivity in substitution reactions to introduce additional functional groups, enabling the study of structure-activity relationships. Additionally, its piperazine moiety is a common structural feature in a number of bioactive compounds, making it an important starting material in the design and synthesis of potential lead compounds in drug discovery projects.
4-Piperazinobenzonitrile (CAS 68104-63-2) References
- Design, synthesis, radiolabeling, and in vivo evaluation of carbon-11 labeled N-[2-[4-(3-cyanopyridin-2-yl)piperazin-1-yl]ethyl]-3-methoxybenzamide, a potential positron emission tomography tracer for the dopamine D(4) receptors. | Lacivita, E., et al. 2010. J Med Chem. 53: 7344-55. PMID: 20873719
- Exploring N-acyl-4-azatetracyclo[5.3.2.02,6.08,10]dodec-11-enes as 11β-HSD1 Inhibitors. | Leiva, R., et al. 2018. Molecules. 23: PMID: 29495550
- Converting non-Mesogenic to Mesogenic Stacking of Amino-s-Triazine-Based Dendrons with p-CN Phenyl Unit by Eliminating Peripheral Dipole. | Lu, YC., et al. 2022. Nanomaterials (Basel). 12: PMID: 35055204
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
4-Piperazinobenzonitrile, 1 g | sc-232969 | 1 g | $99.00 |