Molecular structure of 4-Phenyl-3-furoxancarbonitrile, CAS Number: 125520-62-9
4-Phenyl-3-furoxancarbonitrile (CAS 125520-62-9)
Alternate Names:
Furoxan, RVC-589
Application:
4-Phenyl-3-furoxancarbonitrile is an soluble guanylate cyclase activator
CAS Number:
125520-62-9
Molecular Weight:
187.20
Molecular Formula:
C9H5N3O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Able to activate the soluble guanylate cyclase by releasing Nitric Oxide under the action of thiol cofactors. Also inhibits platelet aggregation.
4-Phenyl-3-furoxancarbonitrile (CAS 125520-62-9) References
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- High-content positional biosensor screening assay for compounds to prevent or disrupt androgen receptor and transcriptional intermediary factor 2 protein-protein interactions. | Hua, Y., et al. 2014. Assay Drug Dev Technol. 12: 395-418. PMID: 25181412
- A new class of furoxan derivatives as NO donors: mechanism of action and biological activity. | Ferioli, R., et al. 1995. Br J Pharmacol. 114: 816-20. PMID: 7773542
- Furoxans as nitric oxide donors. 4-Phenyl-3-furoxancarbonitrile: thiol-mediated nitric oxide release and biological evaluation. | Medana, C., et al. 1994. J Med Chem. 37: 4412-6. PMID: 7996554
- Nitric oxide donors: effects of S-nitrosoglutathione and 4-phenyl-3-furoxancarbonitrile on ocular blood flow and retinal function recovery. | Liu, SX., et al. 1997. J Ocul Pharmacol Ther. 13: 105-14. PMID: 9090611
- New 1,4-dihydropyridines conjugated to furoxanyl moieties, endowed with both nitric oxide-like and calcium channel antagonist vasodilator activities. | Di Stilo, A., et al. 1998. J Med Chem. 41: 5393-401. PMID: 9876109
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GCS.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
4-Phenyl-3-furoxancarbonitrile, 10 mg | sc-206935 | 10 mg | $96.00 |