Date published: 2026-1-31

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4-Palmitamido-2,2,6,6-tetramethylpiperidine-1-oxyl (CAS 22977-65-7)

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Alternate Names:
N-Tempoyl Palmitamide; 4-Palmitamido-TEMPO; 2,2,6,6-Tetramethyl-4-[(1-oxohexadecyl)amino]-1-piperidinyloxy
CAS Number:
22977-65-7
Molecular Weight:
409.67
Molecular Formula:
C25H49N2O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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4-Palmitamido-2,2,6,6-tetramethylpiperidine-1-oxyl (4-PAM-TEMPOL) is an organosulfur compound extensively studied for its role as a free radical scavenger and antioxidant. Its application in scientific research encompasses the investigation of oxidative stress, inflammation, and cell death. The primary function of 4-Palmitamido-2,2,6,6-tetramethylpiperidine-1-oxyl is as a free radical scavenger, effectively neutralizing and preventing damage caused by free radicals to cells and tissues. It achieves this by donating an electron to the free radical, a process known as "reduction." Furthermore, 4-Palmitamido-2,2,6,6-tetramethylpiperidine-1-oxyl acts as an antioxidant, shielding cells and tissues from oxidative damage inflicted by free radicals.


4-Palmitamido-2,2,6,6-tetramethylpiperidine-1-oxyl (CAS 22977-65-7) References

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  4. Probing the effect of the capping polyelectrolyte on the internal structure of Layer-by-Layer decorated nanoliposomes.  |  Mateos-Maroto, A., et al. 2023. J Colloid Interface Sci. 640: 220-229. PMID: 36863179
  5. Properties of mixed monolayers of lecithin and spin probe: I. Study of the interactions at the air-water interface  |  P Chatelain, F Defrise-Quertain… - Journal of Colloid and …, 1979 - Elsevier. November 1979,. Journal of Colloid and Interface Science. Volume 72, Issue 2,: Pages 287-293.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4-Palmitamido-2,2,6,6-tetramethylpiperidine-1-oxyl, 100 mg

sc-478897
100 mg
$388.00