4-(p-Iodophenyl)butyric acid (CAS 27913-58-2)

4-(p-Iodophenyl)butyric acid, known as 4-IPBA, is a significant organic compound extensively explored for its diverse applications in scientific research. Serving as a synthetic, non-steroidal agent, 4-(p-Iodophenyl)butyric acid showcases its value through its ability to inhibit aromatase—an enzyme for estrogen synthesis. Scientific investigations have delved into the potential uses of 4-(p-Iodophenyl)butyric acid, establishing its role as an aromatase inhibitor—an invaluable tool for studying the effects of estrogen within the body. Furthermore, researchers have examined its capacity to modulate the activity of specific enzymes, notably cytochrome P450 enzymes, involved in drug and compound metabolism. Additionally, studies have explored the potential of 4-(p-Iodophenyl)butyric acid in inhibiting the growth of specific cancer cell types. In the realm of aromatase inhibition, 4-(p-Iodophenyl)butyric acid achieves its effects by binding to the enzyme′s active site, effectively impeding the conversion of androgens to estrogens. Its action as a modulator of enzymes, such as cytochrome P450, stems from its binding to the active site, ultimately influencing the enzyme′s activity. The multifaceted properties of 4-(p-Iodophenyl)butyric acid make it a valuable asset in scientific research, facilitating investigations into estrogen-related processes, enzyme modulation, and potential anti-cancer applications.